Paget's disease is a disorder primarily affecting which part of the body?
Muscles
Bones
Skin
Lungs
The Correct Answer is B
Paget's disease is a bone disorder that causes abnormal bone remodeling, leading to enlarged, weak, and deformed bones.
a. Muscles: Paget's disease primarily affects bones, not muscles. While muscles surrounding affected bones may be impacted indirectly, they are not the primary target of the disease.
c. Skin: Paget's disease does not affect the skin. It is a bone disorder and does not involve the skin.
d. Lungs: Paget's disease does not directly affect the lungs. The disease primarily involves bone remodeling, not lung function.
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Correct Answer is C
Explanation
The etiology of Paget's disease involves a combination of genetic factors and environmental triggers. There is evidence of a genetic predisposition, but environmental factors also play a role in the development of the condition. Viral and bacterial infections, as well as dietary deficiencies, are not considered primary causes of Paget's disease.
a. Viral infection: Paget's disease is not caused by a viral infection.
b. Bacterial infection: Paget's disease is not caused by a bacterial infection.
d. Dietary deficiencies: While nutrition is important for bone health, dietary deficiencies are not the primary cause of Paget's disease. Genetic and environmental factors are more influential in its development.
Correct Answer is B
Explanation
Paget's disease commonly affects the axial skeleton, including the skull, spine, and pelvis. The bones in these areas are often involved in the patchy areas of increased bone density and disorganized bone remodeling seen in the condition.
a. Long bones of the extremities: While long bones can be affected by Paget's disease, the axial skeleton is more commonly involved.
c. Hands and feet: The hands and feet can be affected by Paget's disease, but the axial skeleton is more frequently involved.
d. Ribs and sternum: The ribs and sternum can be affected by Paget's disease, but the axial skeleton, including the skull, spine, and pelvis, is more commonly affected.
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