Which of the following differentiates a bacteriostatic drug from a bactericidal drug?
Bacteriostatics are narrow spectrum drugs and bactericidal drugs are broad spectrum
Bacteriostatic drugs inhibit bacterial growth, and bactericidal drugs actually kill bacteria
Bacteriostatics work by inhibiting protein synthesis and bactericidal drugs work by inhibiting nucleic acid synthesis
Bacteriostatic drugs actually kill bacteria and bactericidal drugs inhibit bacterial growth
The Correct Answer is B
A. Bacteriostatics are narrow spectrum drugs, and bactericidal drugs are broad spectrum:
This statement is incorrect. The spectrum of activity (narrow vs. broad) of an antibiotic refers to the range of bacterial species that it can target, not whether it is bacteriostatic or bactericidal.
B. Bacteriostatic drugs inhibit bacterial growth, and bactericidal drugs actually kill bacteria:
This statement is correct. Bacteriostatic drugs work by inhibiting the growth and reproduction of bacteria without directly killing them, whereas bactericidal drugs directly kill bacteria.
C. Bacteriostatics work by inhibiting protein synthesis, and bactericidal drugs work by inhibiting nucleic acid synthesis:
This statement is incorrect. Both bacteriostatic and bactericidal drugs can target various bacterial cellular processes, including protein synthesis, nucleic acid synthesis, cell wall synthesis, and others. The mechanism of action is not a definitive factor in distinguishing between bacteriostatic and bactericidal drugs.
D. Bacteriostatic drugs actually kill bacteria, and bactericidal drugs inhibit bacterial growth:
This statement is incorrect. It contradicts the established definitions of bacteriostatic and bactericidal drugs. Bacteriostatic drugs inhibit bacterial growth without killing the bacteria, while bactericidal drugs directly kill bacteria.
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Related Questions
Correct Answer is B
Explanation
A.Green leafy vegetables:
There is no specific recommendation to avoid green leafy vegetables while taking tetracycline. However, it’s generally advisable to take tetracycline on an empty stomach, as certain foods and supplements containing calcium, magnesium, aluminum, iron, or zinc can interfere with the absorption of tetracycline if consumed concurrently. Green leafy vegetables are not typically high in these minerals, so there is no need to avoid them specifically.
B. Sunlight:
Tetracycline antibiotics, including Sumycin, can increase the skin’s sensitivity to sunlight and UV radiation, leading to an increased risk of sunburn and photosensitivity reactions. Therefore, clients taking tetracycline should be advised to minimize sun exposure, wear protective clothing, and use sunscreen with a high sun protection factor (SPF) to reduce the risk of sunburn and skin damage.
C. Exercise:
There is no specific contraindication to exercise while taking tetracycline. In fact, regular exercise can promote overall health and well-being. However, it’s essential for clients to listen to their bodies and avoid strenuous exercise if they experience any adverse effects or symptoms while taking tetracycline or any other medication.
D. Foods high in tyramine:
Tetracycline antibiotics do not interact with tyramine-containing foods in the same way as certain other classes of antibiotics, such as monoamine oxidase inhibitors (MAOIs). Therefore, there is no specific need to avoid foods high in tyramine while taking tetracycline, as tyramine-related interactions are not typically associated with tetracycline use.
Correct Answer is D
Explanation
A.Alcohol:
Alcohol consumption does not directly reduce the absorption of ciprofloxacin. However, alcohol can interact with certain medications and may exacerbate side effects such as dizziness, drowsiness, and gastrointestinal upset. It’s generally advisable to avoid excessive alcohol consumption while taking ciprofloxacin, but alcohol itself does not significantly affect the absorption of the medication.
B. Intense physical exertion:
Intense physical exertion is unlikely to directly reduce the absorption of ciprofloxacin. However, gastrointestinal motility may increase during intense exercise, potentially affecting the absorption of oral medications. In some cases, gastrointestinal disturbances associated with physical exertion may affect the absorption of ciprofloxacin, but this effect is generally minor and not a significant concern for most individuals.
C. Fruit juices, in particular grapefruit juice:
Grapefruit juice is known to interact with certain medications by inhibiting intestinal enzymes responsible for drug metabolism, leading to increased drug concentrations in the bloodstream. However, ciprofloxacin is not significantly affected by grapefruit juice. In fact, fruit juices, including grapefruit juice, are generally not known to reduce the absorption of ciprofloxacin.
D. Antacids or mineral supplements:
Antacids and mineral supplements containing aluminum, magnesium, calcium, or iron can significantly reduce the absorption of ciprofloxacin when taken concurrently. These substances can form complexes with ciprofloxacin in the gastrointestinal tract, reducing its bioavailability. Therefore, it’s recommended to avoid taking antacids or mineral supplements containing these minerals within a few hours before or after taking ciprofloxacin to avoid interference with its absorption.
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