Which of the following factors are known to commonly trigger a crisis in patients with sickle cell disease? (Select all that apply)

Airplane flights

Dehydration

Cold weather

Illness

Flashing light patterns on television

Answer and Explanation

Correct Answer : A,B,C,D

A.   Airplane flights can trigger a crisis due to changes in altitude and decreased oxygen levels in the cabin. The lower atmospheric pressure and reduced oxygen can contribute to sickling of red blood cells, increasing the risk of a crisis.
B.   Dehydration is a significant trigger for sickle cell crises. It can lead to hemoconcentration, making the blood more viscous and promoting sickling of the red blood cells. Maintaining hydration is crucial for preventing crises.
C.   Exposure to cold weather can trigger vaso-occlusive crises in sickle cell patients. Cold temperatures can cause blood vessels to constrict, reducing blood flow and increasing the likelihood of sickling and pain episodes.
D.   Any illness, particularly infections, can trigger a sickle cell crisis. Infections can lead to increased metabolic demand, dehydration, and inflammatory responses, all of which can contribute to vaso- occlusion and pain.
E.   While certain sensory stimuli can affect individuals with various conditions (like migraines), flashing light patterns on television are not commonly recognized triggers for a sickle cell crisis. There is no substantial evidence linking this to vaso-occlusive events in sickle cell disease.

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Correct Answer is ["A","B","E"]

Explanation

A. A positive antinuclear antibody (ANA) titer is a common finding in SLE. This test is often used as a screening tool for autoimmune diseases, and most patients with SLE will have a positive ANA. Therefore, this finding is expected.
B. The presence of protein in the urine (proteinuria) is indicative of kidney involvement, which can occur in SLE due to lupus nephritis. Given the client's difficulty urinating and other symptoms, this finding would be anticipated.
C. This statement is unlikely to be correct. In SLE, anemia is common due to various factors, including chronic disease, bone marrow involvement, or hemolysis. Therefore, an increased hemoglobin level would not be expected in this scenario.
D. This finding is not typically associated with SLE. SLE is primarily an autoimmune disease affecting the connective tissues, and thyroid function tests (like T3 and T4) would not show increased levels unless there is an underlying thyroid disorder. Therefore, this finding is not expected in SLE.
E. An elevated blood urea nitrogen (BUN) level may be anticipated, especially if there is kidney involvement due to lupus nephritis. Increased BUN can indicate impaired kidney function, which aligns with the client's symptoms of difficulty urinating.

A. Show expected changes in white blood cell counts. B. Skin tests for tuberculosis may be falsely negative. C. Should receive influenza, pneumococcal, and shingles vaccinations. D. Higher risk for respiratory tract and genitourinary infections. E. Booster vaccinations are not likely needed as one ages. F. May not have a fever with severe infection.

Correct Answer is ["B","C","D","F"]

Explanation

A. While it's important for older adults to have regular blood tests to monitor their health, showing expected changes in white blood cell counts is not a specific risk factor for infections.
B. Skin tests for tuberculosis may be falsely negative in older adults due to a weakened immune response.
C. Older adults should stay up-to-date on their vaccinations, including influenza, pneumococcal, and shingles vaccinations, to help protect themselves against these infections.
D. Older adults are at increased risk for respiratory tract infections, such as pneumonia, and genitourinary infections, such as urinary tract infections.
E. Booster vaccinations are essential for older adults to maintain protection against diseases such as influenza, tetanus, diphtheria, and pertussis.
F. Older adults may not develop a fever in response to a severe infection. This can make it difficult to recognize the presence of an infection.

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Which of the following factors are known to commonly trigger a crisis in patients with sickle cell disease? (Select all that apply)

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Naxlex Comprehensive Predictor Exams

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Explanation

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Explanation

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