Which of the following patients is most at risk for liver damage after taking acetaminophen regularly for arthritis pain?
Patient with a history of alcohol abuse and hepatitis C
Patient with COPD and a 20 pack-year history of smoking
Patient with type 2 diabetes and end-stage renal disease
Patient with prostate enlargement and urinary frequency
The Correct Answer is A
Choice A reason: Alcohol and hepatitis C impair liver function; acetaminophen’s metabolite NAPQI accumulates, causing hepatotoxicity in an already compromised organ.
Choice B reason: COPD and smoking affect lungs, not liver; acetaminophen metabolism is minimally impacted, posing lower hepatic risk compared to liver disease states.
Choice C reason: Renal disease affects drug excretion, not liver metabolism; acetaminophen’s hepatic load is unchanged, making liver damage less likely here.
Choice D reason: Prostate issues involve urinary tract; liver metabolism of acetaminophen remains intact, with no heightened risk of hepatotoxicity from this condition.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: Promising instant relief is misleading; most drugs take time, and false expectations may erode trust, reducing cooperation in a toddler’s care.
Choice B reason: Calling it candy is unethical; it risks future candy confusion with drugs, potentially leading to accidental ingestion, unsafe for a 3-year-old.
Choice C reason: Confident explanation suits a toddler’s understanding; it builds trust, reduces fear, and ensures cooperation by clearly stating purpose and process age-appropriately.
Choice D reason: Firm insistence may scare a toddler; without explanation, it lacks reassurance, potentially increasing resistance and distress during medication administration.
Correct Answer is A
Explanation
Choice A reason: Alcohol and hepatitis C impair liver function; acetaminophen’s metabolite NAPQI accumulates, causing hepatotoxicity in an already compromised organ.
Choice B reason: COPD and smoking affect lungs, not liver; acetaminophen metabolism is minimally impacted, posing lower hepatic risk compared to liver disease states.
Choice C reason: Renal disease affects drug excretion, not liver metabolism; acetaminophen’s hepatic load is unchanged, making liver damage less likely here.
Choice D reason: Prostate issues involve urinary tract; liver metabolism of acetaminophen remains intact, with no heightened risk of hepatotoxicity from this condition.
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