The physician gives orders to infuse 1 unit (250 mL) of packed red blood cells over 4 hours. Calculate the flow rate in milliliters per hour.
62.5 mL/hr
125 mL/hr
250 mL/hr
500 mL/hr
The Correct Answer is A
Choice A reason: Flow rate is volume divided by time; 250 mL over 4 hours equals 62.5 mL/hr, ensuring safe transfusion pacing to avoid fluid overload or hemolysis.
Choice B reason: 125 mL/hr assumes 250 mL over 2 hours; this doubles the ordered rate, risking circulatory overload and transfusion reactions in a standard protocol.
Choice C reason: 250 mL/hr infuses the unit in 1 hour; this rapid rate exceeds safe limits, potentially causing hypertension or pulmonary edema in vulnerable patients.
Choice D reason: 500 mL/hr is far too fast, implying 250 mL in 30 minutes; this dangerous speed could trigger severe hemolytic reactions or cardiovascular collapse.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Inhalation targets lungs; transdermal means skin absorption, not respiratory, and this route doesn’t match the prescribed method’s pharmacokinetic profile.
Choice B reason: Transdermal drugs absorb through skin layers; this delivers medication systemically via dermal capillaries, bypassing first-pass metabolism, as intended by the order.
Choice C reason: Rectal administration uses suppositories; transdermal is skin-based, not mucosal, and this route doesn’t align with the prescribed absorption method.
Choice D reason: Sublingual dissolves under the tongue; transdermal is cutaneous, not oral, and this differs entirely from the skin-based delivery system specified.
Correct Answer is B
Explanation
Choice A reason: Lungs excrete volatile drugs like anesthetics; most medications aren’t metabolized here, as they lack the cytochrome enzymes needed for broad drug breakdown.
Choice B reason: The liver is the primary site; cytochrome P450 enzymes metabolize most drugs, converting them into active or excretable forms, critical for pharmacokinetics.
Choice C reason: Kidneys excrete metabolites; they filter, not metabolize, most drugs, relying on prior liver processing, making them secondary in the metabolic pathway.
Choice D reason: The colon absorbs some drugs but doesn’t metabolize most; its role is minimal compared to the liver’s extensive enzymatic drug transformation capacity.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.