Which pathophysiologic events contribute to renal failure associated with tumor lysis syndrome?

Metabolic acidosis.

Elevated white blood cell count.

Crystallization of uric acid in the renal tubules.

Hypocalcemia.

Answer and Explanation

The Correct Answer is C

Choice A rationale
Metabolic acidosis can occur in renal failure but is not directly linked to tumor lysis syndrome.
Choice B rationale
Elevated white blood cell count is not a primary contributor to renal failure in tumor lysis syndrome.
Choice C rationale
Crystallization of uric acid in the renal tubules can obstruct urine flow and cause acute renal failure, which is a direct pathophysiologic event in tumor lysis syndrome.
Choice D rationale
Hypocalcemia is a consequence of tumor lysis syndrome but does not directly cause renal failure.

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Correct Answer is A

Explanation

Choice A rationale
Exercise, in general, is beneficial and should not exacerbate systemic lupus erythematosus (SLE). In fact, regular, gentle exercise can improve overall health and reduce symptoms.
Choice B rationale
Infection can trigger or exacerbate SLE flares by activating the immune system, which can cause increased inflammation.
Choice C rationale
Sunlight exposure can exacerbate SLE due to photosensitivity, leading to skin rashes and triggering systemic flares.
Choice D rationale
Pregnancy can exacerbate SLE due to hormonal changes and the additional strain on the immune system.

A. A raised rash across the nose and face. B. Hypothermia. C. Weight gain. D. Muscle hyperreflexia.

Correct Answer is A

Explanation

Choice A rationale
A raised rash across the nose and face, known as a butterfly rash, is a classic and distinctive manifestation of systemic lupus erythematosus (SLE), often exacerbated by sunlight exposure.
Choice B rationale
Hypothermia is not a common manifestation of SLE; patients more frequently experience fevers due to inflammation and immune system dysregulation.
Choice C rationale
Weight gain is not a typical direct manifestation of SLE; patients might experience weight changes due to medications or complications but not as a primary symptom.
Choice D rationale
Muscle hyperreflexia is not associated with SLE; neurological symptoms in SLE might include seizures or cognitive dysfunction, but not hyperreflexia.

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Which pathophysiologic events contribute to renal failure associated with tumor lysis syndrome?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is teaching a female client who has a new diagnosis of systemic lupus erythematosus (SLE). The nurse should recognize the need for further teaching when the client identifies which of the following as a factor that can exacerbate SLE?

Correct Answer is A

Explanation

A nurse is preparing a presentation at a community center about systemic lupus erythematosus (SLE). The nurse should plan to include which of the following findings as a manifestation of SLE?

Correct Answer is A

Explanation

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