Which pathophysiologic events contribute to renal failure associated with tumor lysis syndrome?

Metabolic acidosis.

Elevated white blood cell count.

Crystallization of uric acid in the renal tubules.

Hypocalcemia.

Answer and Explanation

The Correct Answer is C

Choice A rationale
Metabolic acidosis can occur in renal failure but is not directly linked to tumor lysis syndrome.
Choice B rationale
Elevated white blood cell count is not a primary contributor to renal failure in tumor lysis syndrome.
Choice C rationale
Crystallization of uric acid in the renal tubules can obstruct urine flow and cause acute renal failure, which is a direct pathophysiologic event in tumor lysis syndrome.
Choice D rationale
Hypocalcemia is a consequence of tumor lysis syndrome but does not directly cause renal failure.

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Correct Answer is D

Explanation

Choice A rationale
Liver cancer is not associated with elevated prostate specific antigen (PSA) levels. PSA is a protein produced primarily by prostate cells, and its elevation is typically linked to prostate-related conditions rather than liver disorders.
Choice B rationale
Breast cancer is not associated with elevated PSA levels. PSA is specific to prostate cells, which are not present in breast tissue. Therefore, PSA is not a marker used in diagnosing or monitoring breast cancer.
Choice C rationale
Colon cancer is not linked to elevated PSA levels. PSA is not a biomarker for colon cancer, as it is specific to the prostate gland. Other markers, such as carcinoembryonic antigen (CEA), are more relevant for colon cancer.
Choice D rationale
Prostatic cancer is associated with elevated PSA levels. PSA is produced by prostate cells, and elevated levels can indicate prostate cancer, benign prostatic hyperplasia (BPH), or inflammation of the prostate.

A. "I will avoid crowds to keep from infecting others.”. B. "I will run my toothbrush in the dishwasher every month.”. C. "I will take the antiemetic as soon as the chemotherapy infusion is complete.”. D. "I'll call my doctor if I notice any unusual menstrual bleeding.”.

Correct Answer is D

Explanation

Choice A rationale
Avoiding crowds is to prevent the client from getting infections due to immunosuppression, not to prevent spreading infection to others, thus an incorrect rationale.
Choice B rationale:
Running a toothbrush through a dishwasher may seem hygienic but is generally unnecessary. More effective measures are needed to ensure oral hygiene without excessive sterilization.
Choice C rationale
Antiemetics are typically taken prior to or at the first sign of nausea during chemotherapy, not after the infusion is complete, so this statement is incorrect regarding the timing of antiemetic use.
Choice D rationale
Calling the doctor for unusual menstrual bleeding is crucial as it can indicate thrombocytopenia, a potential side effect of chemotherapy, reflecting the client's correct understanding.

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Which pathophysiologic events contribute to renal failure associated with tumor lysis syndrome?

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Naxlex Comprehensive Predictor Exams

A nurse is evaluating a client's laboratory results. The nurse should recognize that an increase in the client's prostate specific antigen (PSA) laboratory value is indicative of which of the following diagnoses?

Correct Answer is D

Explanation

A nurse is providing teaching to a client who has breast cancer about the adverse effects of chemotherapy. Which of the following client statements indicates an understanding of the teaching?

Correct Answer is D

Explanation

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