Which type of hormone is derived from cholesterol and acts by entering the target cell to influence gene expression?
Catecholamines
Peptide hormones
Thyroid hormones
Steroid hormones
The Correct Answer is D
A. Catecholamines: Catecholamines (such as epinephrine and norepinephrine) are derived from amino acids like tyrosine and act mainly through cell surface receptors, not by entering the cell to affect gene transcription.
B. Peptide hormones: Peptide hormones are chains of amino acids that bind to receptors on the cell surface because they are not lipid-soluble; they act via secondary messenger systems rather than directly influencing DNA transcription.
C. Thyroid hormones: Thyroid hormones are amino acid–derived but are lipid-soluble; they can enter cells and influence gene expression, although they are not cholesterol-derived.
D. Steroid hormones: Steroid hormones (e.g., cortisol, estrogen, testosterone) are synthesized from cholesterol and are lipid-soluble, allowing them to cross the cell membrane, bind intracellular receptors, and regulate gene transcription in the nucleus.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Adrenocorticotropic hormone (ACTH):ACTH stimulates the adrenal cortex to secrete cortisol; overproduction of ACTH causes Cushing disease features rather than the soft-tissue/bone overgrowth seen in acromegaly.
B. Prolactin:Prolactin excess causes galactorrhea and reproductive disturbances; it does not produce the characteristic enlarged hands, feet, and facial features of acromegaly.
C. Thyroid-stimulating hormone (TSH):Excess TSH leads to hyperthyroidism, which causes metabolic and sympathetic symptoms, not the skeletal overgrowth typical of acromegaly.
D. Growth hormone (GH):Excess GH from a pituitary adenoma stimulates increased IGF-1 production, promoting soft-tissue and bone growth that leads to the characteristic enlargement of the hands, feet, and facial bones in acromegaly.
Correct Answer is B
Explanation
A. Monocytes:Monocytes differentiate into macrophages and dendritic cells that perform phagocytosis and antigen presentation but do not produce antibodies.
B. Neutrophils:Neutrophils are short-lived phagocytic cells that ingest and destroy pathogens; they do not produce antibodies.
C. B lymphocytes:B lymphocytes (B cells) differentiate into plasma cells that secrete antibodies specific to antigens, making them the primary source of antibody production.
D. T lymphocytes:T lymphocytes are involved in cell-mediated immunity, regulating immune responses and directly killing infected cells but not in producing antibodies.
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