A 50-year-old male patient presents with facial rounding, central obesity, and purple striae on the abdomen. Laboratory results show high levels of ACTH. What is the most likely underlying cause of his condition?
Adrenal insufficiency.
Pheochromocytoma.
Cushing Disease.
Hyperthyroidism.
The Correct Answer is C
Choice A Reason:
Adrenal insufficiency, also known as Addison’s disease, is characterized by insufficient production of cortisol and aldosterone by the adrenal glands. Symptoms typically include fatigue, weight loss, low blood pressure, and hyperpigmentation of the skin. High levels of ACTH are not associated with adrenal insufficiency; instead, ACTH levels are usually elevated in response to low cortisol levels.
Choice B Reason:
Pheochromocytoma is a rare tumor of the adrenal gland that produces excess catecholamines, leading to symptoms such as hypertension, palpitations, and headaches. It does not cause high levels of ACTH or the physical manifestations described in the patient, such as facial rounding and purple striae.
Choice C Reason:
Cushing Disease is caused by a pituitary adenoma that secretes excess adrenocorticotropic hormone (ACTH), leading to overproduction of cortisol by the adrenal glands. This results in symptoms such as facial rounding (moon face), central obesity, purple striae on the abdomen, and high levels of ACTH. These clinical features align with the patient’s presentation, making Cushing Disease the most likely underlying cause.
Choice D Reason:
Hyperthyroidism is characterized by excessive production of thyroid hormones, leading to symptoms such as weight loss, heat intolerance, palpitations, and tremors. It does not cause high levels of ACTH or the specific physical changes seen in Cushing Disease.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A Reason:
Weight loss is not typically associated with acromegaly. Acromegaly is characterized by excessive growth hormone production, leading to the enlargement of bones and tissues. Patients often experience weight gain rather than loss due to increased bone and soft tissue mass.
Choice B Reason:
Exophthalmos, or bulging eyes, is not a common manifestation of acromegaly. This symptom is more commonly associated with Graves’ disease, a thyroid disorder. Acromegaly primarily affects the bones and soft tissues, leading to changes in facial features and extremities.
Choice C Reason:
Thin and fragile hair is not a typical symptom of acromegaly. While hormonal imbalances can affect hair quality, acromegaly is more commonly associated with changes in bone and soft tissue structure. Symptoms like coarse, oily skin and excessive sweating are more characteristic of this condition.
Choice D Reason:
Enlarged hands and feet are hallmark signs of acromegaly. The excessive production of growth hormone leads to the enlargement of bones in the hands, feet, and face. Patients may notice that their rings no longer fit and that their shoe size has increased. This symptom is a key indicator of acromegaly and is often used in the diagnosis of the condition.
Correct Answer is A
Explanation
Choice A Reason:
Tonometry is a diagnostic test that measures the intraocular pressure (IOP) inside the eye. This measurement is crucial for detecting and managing glaucoma, as elevated IOP is a significant risk factor for the disease. By measuring the pressure, healthcare providers can assess the risk of optic nerve damage and initiate appropriate treatments to prevent vision loss.
Choice B Reason:
Tonometry does not allow for the inspection of the optic disc for signs of degeneration. This function is typically performed using ophthalmoscopy or optical coherence tomography (OCT), which provide detailed images of the optic nerve and retina. These tests are essential for evaluating the structural damage caused by glaucoma but are not part of the tonometry procedure.
Choice C Reason:
Tonometry is not performed to evaluate peripheral vision. Peripheral vision is assessed using perimetry or visual field testing, which maps the field of vision and detects areas of vision loss. This test helps determine the extent of visual impairment caused by glaucoma but is separate from tonometry.
Choice D Reason:
Tonometry does not diagnose the type of glaucoma. While it measures intraocular pressure, diagnosing the specific type of glaucoma requires a comprehensive eye examination, including gonioscopy to examine the drainage angle of the eye and other tests to assess optic nerve health and visual field. Therefore, tonometry is just one component of the diagnostic process.
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