A 74-year-old man with cirrhosis is admitted to the hospital and he has started taking a diuretic. Which age-related change may result in decreased drug clearance in this patient?
Decreased blood flow to the liver
Increased body fat
Decreased serum albumin
Decreased body water
The Correct Answer is A
A. Decreased blood flow to the liver: Aging reduces hepatic perfusion, impairing the liver’s ability to metabolize drugs, especially in patients with liver disease.
B. Increased body fat: This affects the distribution of fat-soluble drugs but not clearance.
C. Decreased serum albumin: This affects protein binding and distribution of certain drugs but not clearance directly.
D. Decreased body water: This influences water-soluble drug distribution, not drug clearance.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Fear
May be present, but persistent withdrawal is more characteristic of depression.
B. Stubbornness
Labeling the behavior as stubborn overlooks underlying psychological concerns.
C. Exhaustion
Fatigue may contribute, but alone does not fully explain the behavioral pattern.
D. Depression
Social withdrawal, appetite changes, and lack of interest are common signs of depression in older adults.
Correct Answer is C
Explanation
A. a person's state of mind: This refers to subjective perception, not a universal definition.
B. a progressive decline in cognitive function: Cognitive decline is not inevitable in aging and is not a defining characteristic of aging.
C. the process of growing older or more mature: This is the best and most accurate general definition of aging.
D. the process of slowing down: This may occur with aging, but it is not a complete or defining description.
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