A cancer patient asks the nurse what can be given to alleviate severe, chronic pain of several months’ duration. The patient has been taking oxycodone (OxyContin) and states it is no longer effective. The nurse will suggest discussing which medication with the provider?
Pentazocine (Talwin) PO
Hydrocodone (Vicodin) PO
Fentanyl (Duragesic) transdermal patch
Meperidine (Demerol) PO
The Correct Answer is C
Choice A reason: Pentazocine is less effective for severe, chronic pain and has mixed agonist-antagonist effects. Fentanyl is stronger for opioid-tolerant patients, so this is incorrect.
Choice B reason: Hydrocodone is weaker than oxycodone and inadequate for severe, resistant pain. Fentanyl’s potency suits chronic cancer pain, so this is incorrect.
Choice C reason: Fentanyl transdermal is potent, long-acting, and ideal for severe, chronic cancer pain in opioid-tolerant patients. It’s appropriate here, making it the correct choice.
Choice D reason: Meperidine is not recommended for chronic pain due to neurotoxic metabolites. Fentanyl is safer and more effective, so this is incorrect.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Drug-receptor binding either activates (agonists) or inhibits (antagonists) receptor activity, altering physiological responses. This is the primary effect, making it the correct choice for receptor interaction.
Choice B reason: Drugs do not permanently alter receptors non-responsive; they modulate activity temporarily. Non-responsiveness may occur with chronic use, but it’s not the primary effect, so this is incorrect.
Choice C reason: Preventing receptor action is specific to antagonists, not all drugs. drugs bind to receptors. Binding broadly affects activity, so this is incorrect for the general effect of receptor binding.
Choice D reason: Drugs do not give receptors new functions; they enhance or block existing ones. ones. Activity modulation is the key effect, making this incorrect for what occurs during binding.
Correct Answer is B
Explanation
Choice A reason: Beta blockers decrease renin release, reducing angiotensin II and aldosterone, which lowers blood pressure. This statement is accurate, reflecting correct understanding, so it does not indicate a need for further teaching.
Choice B reason: Beta blockers do not primarily decrease peripheral vascular resistance; they reduce heart rate and contractility. Peripheral resistance is more affected by alpha blockers or vasodilators, so this incorrect statement indicates a need for further teaching.
Choice C reason: Beta blockers reduce heart rate and myocardial contractility, decreasing cardiac output and blood pressure. This statement is correct, showing proper understanding, so it does not require additional teaching.
Choice D reason: While beta blockers do not directly block angiotensin II, they reduce its production by decreasing renin. The statement is imprecise but not entirely wrong, making it less indicative of a teaching need than choice B.
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