A client is concerned about the risk of developing cholecystitis due to a family history of gallstones. Which of the following explanations should the nurse provide regarding the genetic predisposition to gallstone formation?

Choice A reason:

Dark urine and pale-colored stools are not typically associated with a gastrointestinal infection. These symptoms are more indicative of changes in bile flow or bilirubin excretion.

Choice B reason:

While cholecystitis can lead to malabsorption of nutrients, it is not the primary cause of changes in stool color to pale.

Choice C reason:

This statement is correct. Cholecystitis can obstruct the bile duct, leading to a decrease in bilirubin excretion. Bilirubin gives urine its characteristic color, and when excretion is reduced, the urine becomes darker (brownish). Likewise, the absence of bilirubin in the stool leads to pale-colored or clay-colored stools.

Choice D reason:

Dehydration may occur in some cases of cholecystitis, but it is not the primary cause of changes in urine and stool color.

Choice A reason:

Rebound tenderness in the right upper quadrant is not a hallmark sign of acute cholecystitis. It may be present in conditions such as appendicitis or peritonitis.

Choice B reason:

This statement is correct. Murphy's sign is a hallmark sign of acute cholecystitis. It is elicited by asking the client to take a deep breath while the nurse palpates the right upper quadrant. If the client abruptly stops breathing due to pain upon palpation, it indicates inflammation of the gallbladder (positive Murphy's sign).

Choice C reason:

Hypoactive bowel sounds may be present in some gastrointestinal conditions but are not specific to acute cholecystitis.

Choice D reason:

Left lower quadrant abdominal pain is not associated with acute cholecystitis. This type of pain is more commonly seen in conditions such as diverticulitis or colitis.