A client is inquiring about the genetic basis of cystic fibrosis (CF). Which statement by the nurse provides an accurate explanation?
"CF is caused by a dominant genetic mutation that always manifests in affected individuals."
"CF results from the presence of two recessive genetic mutations, one inherited from each parent."
"CF is due to a spontaneous genetic mutation that occurs during a person's lifetime."
"CF is exclusively caused by environmental factors and is not related to genetics."
The Correct Answer is B
A) Incorrect. CF is an autosomal recessive genetic disorder, meaning that both copies of the CFTR gene must carry a mutation for the condition to manifest.
B) Correct. CF is caused by the inheritance of two recessive genetic mutations, one from each parent, resulting in defective CFTR protein function.
C) Incorrect. CF is primarily a genetic disorder present from birth, not one caused by spontaneous mutations during a person's lifetime.
D) Incorrect. CF is primarily a genetic disorder with well-established genetic mutations associated with its development.
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Related Questions
Correct Answer is C
Explanation
A) Incorrect. CF primarily affects the pancreas and small intestine, not the stomach.
B) Incorrect. While liver complications can occur in some individuals with CF, such as liver disease or cirrhosis, it is not a primary manifestation of the disease.
C) Correct. CF often results in thickened mucus obstructing the pancreatic ducts, causing pancreatic insufficiency and malabsorption of essential nutrients.
D) Incorrect. CF primarily affects the pancreas and small intestine rather than the large intestine, and chronic constipation is not a typical symptom of CF.
Correct Answer is D
Explanation
A) Incorrect. Postural drainage involves positioning the body to help drain mucus but does not use a mechanical device.
B) Incorrect. Autogenic drainage is a technique that involves controlled breathing and airflow, not a mechanical device.
C) Incorrect. PEP therapy uses a device to provide positive pressure during exhalation but is different from HFCWO.
D) Correct. High-frequency chest wall oscillation (HFCWO) involves using a mechanical device to deliver oscillations to the chest wall, helping to mobilize and clear mucus from the airways.
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