A nurse is explaining the pathophysiology of cystic fibrosis (CF) to a newly diagnosed patient. Which statement accurately describes the genetic basis of CF?
"CF results from a dominant genetic mutation inherited from one parent."
"CF occurs due to the presence of two dominant genetic mutations."
"CF is caused by a recessive genetic mutation inherited from both parents."
"CF is a non-genetic condition caused by environmental factors."
The Correct Answer is C
A) Incorrect. CF is an autosomal recessive genetic disorder, meaning that both copies of the CFTR gene must carry a mutation for the condition to manifest.
B) Incorrect. CF is not caused by dominant genetic mutations.
C) Correct. CF results from inheriting two recessive genetic mutations, one from each parent, leading to defective CFTR protein function.
D) Incorrect. CF is primarily a genetic disorder with well-established genetic mutations associated with its development.
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Related Questions
Correct Answer is C
Explanation
A) Incorrect. While monitoring carbohydrate intake is important in CF, limiting carbohydrates is not the primary focus of nutrition management.
B) Incorrect. Increasing sodium intake is not a general recommendation for individuals with CF; it depends on the individual's needs.
C) Correct. Individuals with CF often require a high-calorie diet rich in fats and proteins to address malabsorption and maintain adequate nutrition.
D) Incorrect. Restricting fluid intake is not recommended for individuals with CF, as staying hydrated is important for preventing thickening of mucus.
Correct Answer is D
Explanation
A) Incorrect. If both parents are carriers, their child's risk of having CF is 25%, not 50%.
B) Incorrect. While the risk is increased, having two carrier parents does not guarantee that a child will have CF.
C) Incorrect. If both parents are carriers, their child can inherit two normal genes (no CF), one normal and one CF gene (carrier status), or two CF genes (CF).
D) Correct. When both parents are carriers, there is a 25% chance that their child will inherit two CF genes and have CF, a 50% chance of being a carrier, and a 25% chance of inheriting two normal genes (no CF).
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