A client is using chamomile tea as a remedy to treat gastrointestinal upset.
When discussing the use of this herb, the nurse would alert the client that contact dermatitis is a possibility if the client has a hypersensitivity to which of the following plants?

Choice A rationale:

Alkylating agents are cell cycle-specific drugs. They work on cells during various stages of the cell cycle and are classified as cell cycle phase-nonspecific drugs. These drugs form covalent bonds with DNA, preventing DNA replication and transcription. This action disrupts the cell cycle, making them effective against actively dividing cells.

Choice B rationale:

Plant alkaloids are not cell cycle-specific drugs. Plant alkaloids, such as vinblastine and vincristine, are derived from plants and are classified as cell cycle phase-specific drugs. They primarily affect cells during the M phase of the cell cycle by disrupting microtubule formation. While they are effective against rapidly dividing cells, they are not cell cycle-specific.

Choice C rationale:

Antineoplastic antibiotics are not cell cycle-specific drugs. These drugs, such as doxorubicin and daunorubicin, are used in cancer treatment and primarily work by intercalating with DNA and inhibiting topoisomerase enzymes. Their mechanisms of action do not specifically target a particular phase of the cell cycle, making them cell cycle phase-nonspecific.

Choice D rationale:

Retinoids are not cell cycle-specific drugs. Retinoids are derived from vitamin A and have various mechanisms of action, including regulating cell growth and differentiation. They are not classified as cell cycle-specific drugs.