The parents of a child who is recovering from chickenpox tell the nurse that they gave the child aspirin for his fever.
The nurse would be alert to the development of which of the following?

Choice A rationale:

Emetics are medications that induce vomiting and are used in cases of drug overdose, ingestion of toxic substances, or other situations where rapid removal of the ingested substance is necessary. However, it is crucial that the client's mental status is intact and they can cooperate and understand the need to induce vomiting. If a client is unconscious or unable to protect their airway, inducing vomiting can lead to aspiration and further complications.

Choice B rationale:

Clients with existing severe hypertension should not be administered emetics, as the act of inducing vomiting can lead to a sudden increase in blood pressure, potentially causing adverse cardiovascular events.

Choice C rationale:

Clients with a medical history of convulsions (seizures) should not be given emetics. Inducing vomiting may lead to a convulsive episode, which can be harmful and increase the risk of aspiration.

Choice D rationale:

Clients with an existing condition of hemorrhagic diathesis (a tendency to bleed excessively) should not be administered emetics. Inducing vomiting can cause mucosal damage and bleeding in the gastrointestinal tract, further exacerbating the client's condition.

Choice A rationale:

Alkylating agents are cell cycle-specific drugs. They work on cells during various stages of the cell cycle and are classified as cell cycle phase-nonspecific drugs. These drugs form covalent bonds with DNA, preventing DNA replication and transcription. This action disrupts the cell cycle, making them effective against actively dividing cells.

Choice B rationale:

Plant alkaloids are not cell cycle-specific drugs. Plant alkaloids, such as vinblastine and vincristine, are derived from plants and are classified as cell cycle phase-specific drugs. They primarily affect cells during the M phase of the cell cycle by disrupting microtubule formation. While they are effective against rapidly dividing cells, they are not cell cycle-specific.

Choice C rationale:

Antineoplastic antibiotics are not cell cycle-specific drugs. These drugs, such as doxorubicin and daunorubicin, are used in cancer treatment and primarily work by intercalating with DNA and inhibiting topoisomerase enzymes. Their mechanisms of action do not specifically target a particular phase of the cell cycle, making them cell cycle phase-nonspecific.

Choice D rationale:

Retinoids are not cell cycle-specific drugs. Retinoids are derived from vitamin A and have various mechanisms of action, including regulating cell growth and differentiation. They are not classified as cell cycle-specific drugs.