A client previously experienced a severe anaphylactic reaction to penicillin G. Which medication class should not be administered to this client due to the potential for cross-sensitivity?

A. This insulin does not peak like short-acting insulin; glargine provides a consistent release of insulin without a peak effect.

B. Long-acting insulin is not meant to be taken with meals, as it provides basal control and is typically taken once daily, not with each meal.

C. This statement is correct; glargine provides a steady level of insulin over 24 hours, helping to maintain consistent blood glucose levels throughout the day and night.

D. Long-acting insulin is usually administered once daily, so stating that it must be given three times a day is incorrect.

A. Decreased appetite may occur but is not the most critical concern in this context.

B. The combination of metoclopramide, which can influence serotonin pathways, with certain antidepressants, especially SSRIs, increases the risk of serotonin syndrome, a potentially life-threatening condition.

C. While some antidepressants can influence blood pressure, monitoring for elevated blood pressure is not the primary concern with metoclopramide.

D. There is no evidence to suggest that metoclopramide enhances the effects of antidepressants; the focus should be on potential adverse interactions instead.