A client with peripheral vascular disease (PAD) is prescribed cilostazol, a medication that improves blood flow in the legs. The nurse should instruct the client to:

For a client with peripheral vascular disease (PAD) who is prescribed cilostazol, the nurse should provide the following instruction:

C) Avoid grapefruit juice while on cilostazol.

Grapefruit juice can interact with certain medications, including cilostazol, and may lead to increased levels of the medication in the bloodstream. This can potentially cause adverse effects or interfere with the intended therapeutic effects of cilostazol. Therefore, clients taking cilostazol should be advised to avoid grapefruit juice.

The other options are not appropriate:

A) Increasing the dosage of cilostazol without consulting a healthcare provider is not recommended and can be dangerous.

B) Cilostazol can be taken with or without food, so taking it on an empty stomach is not necessary.

D) While compression stockings can be used for some individuals with PAD, their use should be discussed with the healthcare provider and is not specific to cilostazol instructions.

A) This choice is incorrect because hypertension (high blood pressure) is not a significant risk factor for venous insufficiency. Venous insufficiency involves the impairment of venous valves and blood flow in the veins, not arterial hypertension.

B) This choice is incorrect because atherosclerosis is associated with peripheral artery disease (PAD), not venous insufficiency. Atherosclerosis involves the buildup of plaque in the arteries, leading to reduced blood flow in the extremities.

C) This choice is correct. Deep vein thrombosis (DVT) is a condition where a blood clot forms in a deep vein, most commonly in the legs. DVT can lead to damage to the venous valves and veins, causing venous insufficiency and complications such as chronic venous insufficiency and venous ulcers.

D) This choice is incorrect because Raynaud's disease primarily affects the fingers and toes, causing them to spasm and change color in response to cold or stress. It is not directly related to the development of venous insufficiency.