A couple comes into the clinic for genetic counseling. Both parents are heterozygous for sickle cell trait. What is the chance each of their children will have sickle cell anemia?
50%
25%
75%
100%
The Correct Answer is B
The correct answer is b. 25%.
Choice A: 50%
If both parents are heterozygous for the sickle cell trait (carriers), each child has a 50% chance of inheriting one sickle cell gene from one parent and a normal gene from the other parent. This would make the child a carrier of the sickle cell trait, not someone with sickle cell anemia. Therefore, the chance of having sickle cell anemia is not 50%.
Choice B: 25%
When both parents are carriers of the sickle cell trait (heterozygous), there is a 25% chance that their child will inherit two sickle cell genes (one from each parent), resulting in sickle cell anemia. This is because each parent has one normal hemoglobin gene (A) and one sickle cell gene (S). The possible combinations for their children are AA (normal), AS (carrier), SA (carrier), and SS (sickle cell anemia). The probability of the SS combination is 25%.
Choice C: 75%
A 75% chance is not accurate in this scenario. The 75% figure might be mistakenly considered if one were to add the probabilities of being a carrier (50%) and having sickle cell anemia (25%). However, these probabilities are distinct and should not be combined in this manner.
Choice D: 100%
A 100% chance would imply that every child of the couple would have sickle cell anemia, which is not the case. Since each parent is a carrier, there is only a 25% chance for each child to have sickle cell anemia. The remaining 75% of the time, the child will either be a carrier or have normal hemoglobin.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason:
Decreased abdominal distention is not typically a sign of appendicitis perforation. In fact, perforation often leads to increased abdominal distention due to the release of intestinal contents into the abdominal cavity, causing inflammation and swelling. Therefore, this choice is incorrect.
Choice B reason:
Anorexia, or loss of appetite, is a common symptom of appendicitis but not specifically indicative of perforation2. While anorexia can be present in cases of perforation, it is not a definitive sign. The sudden relief of pain is a more critical indicator of perforation, as it suggests the appendix has ruptured, temporarily relieving pressure.
Choice C reason:
Bradycardia, or a slow heart rate, is not a typical sign of appendicitis perforation. In fact, appendicitis and its complications, such as perforation, are more likely to cause tachycardia (an increased heart rate) due to pain and infection. Therefore, this choice is incorrect.
Choice D reason:
Sudden relief from pain is a classic sign of appendicitis perforation. When the appendix ruptures, the pressure inside the appendix is relieved, leading to a temporary decrease in pain. However, this is followed by a rapid onset of severe pain as the contents of the appendix spread throughout the abdominal cavity, causing peritonitis. This sudden change in pain is a critical indicator that the appendix has perforated and requires immediate medical attention.
Correct Answer is C
Explanation
Choice A reason:
A diet consisting of low-fat, low-carbohydrate foods is not specifically recommended for managing severe edema associated with acute glomerulonephritis. While a balanced diet is important, the primary dietary focus should be on reducing sodium intake to prevent fluid retention and manage edema. Therefore, this choice is not the most appropriate recommendation.
Choice B reason:
Decreasing the number of calories in the child’s diet is not a primary recommendation for managing severe edema associated with acute glomerulonephritis. The focus should be on reducing sodium intake rather than calorie restriction. Adequate nutrition is essential for the child’s overall health and recovery1. Therefore, this choice is not the most appropriate recommendation.
Choice C reason:
Avoiding adding salt to the child’s food is a key recommendation for managing severe edema associated with acute glomerulonephritis. Sodium can lead to water retention, which can worsen edema and increase blood pressure. A low-sodium diet helps to reduce fluid retention and manage the symptoms of glomerulonephritis. This is the most appropriate dietary recommendation for managing severe edema in this condition.
Choice D reason:
Increasing the amount of protein in the child’s diet is not recommended for managing severe edema associated with acute glomerulonephritis1. In fact, protein intake may need to be monitored and possibly restricted to prevent the buildup of waste products in the blood1. The primary dietary focus should be on reducing sodium intake to manage edema. Therefore, this choice is not the most appropriate recommendation.
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