A couple comes into the clinic for genetic counseling. Both parents are heterozygous for sickle cell trait. What is the chance each of their children will have sickle cell anemia?
50%
25%
75%
100%
The Correct Answer is B
The correct answer is b. 25%.
Choice A: 50%
If both parents are heterozygous for the sickle cell trait (carriers), each child has a 50% chance of inheriting one sickle cell gene from one parent and a normal gene from the other parent. This would make the child a carrier of the sickle cell trait, not someone with sickle cell anemia. Therefore, the chance of having sickle cell anemia is not 50%.
Choice B: 25%
When both parents are carriers of the sickle cell trait (heterozygous), there is a 25% chance that their child will inherit two sickle cell genes (one from each parent), resulting in sickle cell anemia. This is because each parent has one normal hemoglobin gene (A) and one sickle cell gene (S). The possible combinations for their children are AA (normal), AS (carrier), SA (carrier), and SS (sickle cell anemia). The probability of the SS combination is 25%.
Choice C: 75%
A 75% chance is not accurate in this scenario. The 75% figure might be mistakenly considered if one were to add the probabilities of being a carrier (50%) and having sickle cell anemia (25%). However, these probabilities are distinct and should not be combined in this manner.
Choice D: 100%
A 100% chance would imply that every child of the couple would have sickle cell anemia, which is not the case. Since each parent is a carrier, there is only a 25% chance for each child to have sickle cell anemia. The remaining 75% of the time, the child will either be a carrier or have normal hemoglobin.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason:
I will have my child rest: Resting is an important part of managing a bleeding episode in children with hemophilia. It helps to minimize movement and reduce the risk of further injury or bleeding.
Choice B Reason:
I will compress the site: Applying pressure to the bleeding site is a standard first aid measure for controlling bleeding. Compression helps to slow down or stop the bleeding by promoting clot formation.
Choice C Reason:
I will apply heat: Applying heat is not recommended for managing bleeding in hemophilia. Heat can increase blood flow to the area, potentially worsening the bleeding. Instead, cold compresses or ice packs should be used to constrict blood vessels and reduce bleeding.
Choice D Reason:
I will elevate the affected part: Elevating the affected limb can help reduce blood flow to the area and minimize bleeding. This is a common and effective first aid measure for managing bleeding episodes.
Correct Answer is B
Explanation
Choice A reason:
Hypokalemia, or low potassium levels, is not typically associated with chronic renal failure. In fact, chronic renal failure often leads to hyperkalemia, which is an elevated level of potassium in the blood. This occurs because the kidneys are unable to excrete potassium effectively, leading to its accumulation in the body. Therefore, hypokalemia is not a clinical manifestation of chronic renal failure.
Choice B reason:
Oliguria, or reduced urine output, is a common clinical manifestation of chronic renal failure2. As the kidneys lose their ability to filter and excrete waste products, urine production decreases. This reduction in urine output is a key indicator of declining kidney function and is often observed in children with chronic renal failure. Monitoring urine output is crucial in assessing the progression of the disease and the effectiveness of treatment.
Choice C reason:
Hypotension, or low blood pressure, is not typically seen in chronic renal failure. Instead, hypertension, or high blood pressure, is more commonly associated with chronic renal failure. The kidneys play a crucial role in regulating blood pressure, and when they are not functioning properly, it can lead to an increase in blood pressure. Therefore, hypotension is not a clinical manifestation of chronic renal failure.
Choice D reason:
Massive hematuria, or the presence of a large amount of blood in the urine, is not a typical clinical manifestation of chronic renal failure. While hematuria can occur in some kidney conditions, it is not a defining feature of chronic renal failure. Chronic renal failure is more commonly associated with symptoms such as oliguria, fatigue, and swelling due to fluid retention.
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