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A doctor orders Vancomycin 500 mg to infuse at 5 mg/kg/hr. The patient weighs 98 lbs. You are supplied with a 500 mg/100 mL bag. How many mL/hr will you administer? (Round your answer to the nearest tenths)

A.

44 mL/dose

B.

44.5 mL/hr

C.

44.50 mL/dose

D.

44 units

Answer and Explanation

The Correct Answer is B

Given:

Ordered dose of Vancomycin: 500 mg

Infusion rate: 5 mg/kg/hr

Patient weight: 98 lbs

Concentration of Vancomycin: 500 mg/100 mL

 

Step 1: Convert patient weight from pounds to kilograms:

1 pound (lb) = 0.453592 kilograms (kg)

Patient weight in kg = 98 lbs x 0.453592 kg/lb = 44.462256 kg

 

Step 2: Calculate the total dose of Vancomycin in mg/hr:

Total dose (mg/hr) = Ordered dose (mg/kg/hr) x Patient weight (kg)

Total dose (mg/hr) = 5 mg/kg/hr x 44.462256 kg

Total dose (mg/hr) = 222.31128 mg/hr

 

Step 3: Calculate the infusion rate in mL/hr:

Infusion rate (mL/hr) = Total dose (mg/hr) / Concentration (mg/mL)

Infusion rate (mL/hr) = 222.31128 mg/hr / (500 mg/100 mL)

Infusion rate (mL/hr) = 222.31128 mg/hr x (100 mL/500 mg)

Infusion rate (mL/hr) = 44.462256 mL/hr

 

Step 4: Round to the nearest tenth:

Infusion rate (mL/hr) ≈ 44.5 mL/hr


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Related Questions

Correct Answer is B

Explanation

Given:
Volume of fluid: 30 mL
Infusion time: 20 minutes

Step 1: Convert infusion time to hours:
Infusion time (hr) = 20 min / 60 min/hr
Infusion time (hr) = 0.33 hr

Step 2: Calculate the infusion rate in mL/hr:
Flow rate (mL/hr) = Volume (mL) / Infusion time (hr)
Flow rate (mL/hr) = 30 mL / 0.33 hr
Flow rate (mL/hr) = 90.90909091 mL/hr

Step 3: Round to the nearest whole number:
Flow rate (mL/hr) ≈ 90 mL/hr

Correct Answer is C

Explanation

A) Simvastatin:
Simvastatin is a medication used to lower cholesterol levels by inhibiting HMG-CoA reductase, an enzyme involved in the production of cholesterol in the liver. It is not an angiotensin-converting enzyme (ACE) inhibitor. Therefore, it does not have a direct effect on blood pressure or the renin-angiotensin system.

B) Losartan:
Losartan is an angiotensin II receptor blocker (ARB), not an ACE inhibitor. Like ACE inhibitors, ARBs are used to treat conditions like hypertension and heart failure, but they work differently by blocking the receptors that angiotensin II binds to, rather than inhibiting the enzyme that converts angiotensin I to angiotensin II.

C) Quinapril:
Quinapril is an ACE inhibitor. ACE inhibitors block the enzyme angiotensin-converting enzyme, which converts angiotensin I into angiotensin II, a potent vasoconstrictor. By inhibiting this conversion, ACE inhibitors like quinapril help lower blood pressure, reduce strain on the heart, and treat conditions like hypertension and heart failure.

D) Metoprolol:
Metoprolol is a beta-blocker, not an ACE inhibitor. It works by blocking beta-adrenergic receptors in the heart, which helps to lower heart rate and blood pressure. It is often used in the management of hypertension, heart failure, and to prevent heart attacks, but it does not affect the renin-angiotensin system like ACE inhibitors.

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