A nurse is administering a medication with a half-life of 6 hours. If the initial dose is 800 mg, how much of the medication will remain in the patient's system after 18 hours?
300 mg
400 mg
200 mg
100 mg
The Correct Answer is D
A. 300mg is incorrect.
B. 400mg is incorrect
C. 200mg is incorrect
D. The half-life of a drug is the time it takes for the plasma concentration of a drug to decrease by 50%. If the half-life is 6 hours, the amount of drug in the body will halve every 6 hours.
- Initial dose: 800 mg
- After 6 hours (1st half-life): 800 mg ÷ 2 = 400 mg
- After 12 hours (2nd half-life): 400 mg ÷ 2 = 200 mg
- After 18 hours (3rd half-life): 200 mg ÷ 2 = 100 mg
After 18 hours (three half-lives), 100 mg of the medication will remain in the patient's system.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Request an order for an antiemetic: Although nausea is a symptom of digoxin toxicity, administering an antiemetic may mask a serious underlying problem. It should not be the first intervention without further assessment of the client’s condition.
B. Check the client's vital signs: Digoxin toxicity can cause bradycardia, hypotension, and arrhythmias. The client's symptoms (nausea, weakness, and visual disturbances) are classic signs of digoxin toxicity. Assessing vital signs is the priority to determine if there is immediate hemodynamic instability, which would guide further urgent interventions.
C. Suggest that the client rests before eating the meal: Fatigue may be related to digoxin toxicity or underlying heart failure, but suggesting rest delays necessary clinical assessment and does not address the potentially serious symptoms.
D. Request a dietitian consult: While nutrition is important for clients with CHF, the presence of nausea, weakness, and visual disturbances suggests possible digoxin toxicity, which requires immediate clinical evaluation not dietary consultation.
Correct Answer is D
Explanation
A. Donepezil cures Alzheimer's disease: There is currently no cure for Alzheimer's disease. Donepezil does not halt or reverse the disease process; it only manages symptoms for a limited period in some patients.
B. Donepezil prevents the progression of Alzheimer’s disease: Donepezil does not prevent the neurodegenerative progression of Alzheimer’s. The disease will continue to advance despite treatment, although symptoms may be temporarily improved.
C. Donepezil reverses Alzheimer’s disease: Alzheimer's-related brain damage is irreversible, and Donepezil cannot regenerate lost neurons or restore lost function. It may slightly improve cognitive function but cannot reverse the disease process.
D. Donepezil provides symptom relief for Alzheimer’s disease: Donepezil is a cholinesterase inhibitor that increases acetylcholine levels in the brain, temporarily improving cognitive symptoms like memory and awareness. It is approved for symptom management, especially in mild to moderate stages.
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