A nurse is administering an antidepressant medication to a client. The nurse should understand that which of the following is the major difference between selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs)?

SSRIs are more effective in relieving manifestations.

SSRIs produce a more sedative effect.

TCAs are lethal in overdose.

TCAs have fewer cardiovascular effects.

Answer and Explanation

The Correct Answer is C

A reason: SSRIs are more effective in relieving manifestations. Both SSRIs and TCAs are effective in treating depression, but SSRIs are generally preferred due to their more favorable side effect profile. Effectiveness can vary among individuals, so this statement is not a significant differentiator.

B reason: SSRIs produce a more sedative effect. SSRIs are generally less sedating than TCAs. TCAs are known for their sedative properties and are often prescribed for clients who need help with insomnia related to depression.

C reason: TCAs are lethal in overdose. One major difference between TCAs and SSRIs is the toxicity level in overdose. TCAs can be lethal in overdose due to their cardiotoxic effects, making them more dangerous compared to SSRIs, which have a lower risk of toxicity.

D reason: TCAs have fewer cardiovascular effects. TCAs have more cardiovascular side effects, such as arrhythmias and orthostatic hypotension, compared to SSRIs. This statement is incorrect as TCAs are associated with higher cardiovascular risks.

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Correct Answer is B

Explanation

A reason: Midazolam. Midazolam is a benzodiazepine used for sedation, anxiety relief, and seizure management. It is not typically used as a first-line treatment for major depressive disorder.

B reason: Fluoxetine. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) commonly prescribed as a first-line treatment for major depressive disorder. It helps increase serotonin levels in the brain, which can improve mood and alleviate depressive symptoms.

C reason: Cyclobenzaprine. Cyclobenzaprine is a muscle relaxant used to relieve muscle spasms. It is not indicated for the treatment of major depressive disorder.

D reason: Valproic acid. Valproic acid is a mood stabilizer primarily used to treat bipolar disorder and seizure disorders. It is not typically used as a first-line treatment for major depressive disorder.

A. Polyphagia. B. Fever. C. Bradycardia. D. Oliguria.

Correct Answer is B

Explanation

A reason: Polyphagia. Polyphagia, or excessive eating, is not typically associated with cocaine use. Cocaine often suppresses appetite rather than increasing it.

B reason: Fever. Cocaine use can lead to hyperthermia or elevated body temperature due to increased metabolic activity and stimulation of the central nervous system.

C reason: Bradycardia. Bradycardia, or a slow heart rate, is not a typical response to cocaine use. Cocaine is a stimulant that usually causes tachycardia, or a rapid heart rate.

D reason: Oliguria. Oliguria, or reduced urine output, is not a typical finding associated with acute cocaine use. The drug's immediate effects are more related to cardiovascular and neurological systems.

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A nurse is administering an antidepressant medication to a client. The nurse should understand that which of the following is the major difference between selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs)?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is caring for a client who has a new diagnosis of major depressive disorder. Which of the following medications should the nurse expect the provider to prescribe to the client as a first-line treatment?

Correct Answer is B

Explanation

A nurse is assessing a client who reports using cocaine 1 hour ago. Which of the following findings should the nurse expect?

Correct Answer is B

Explanation

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