A nurse is assessing a client who is receiving androgen therapy to treat endometriosis.
For which of the following adverse effects should the nurse monitor?
Weight loss.
Hypotension.
Muscle hypertrophy.
Edema.
The Correct Answer is D
Choice A rationale
Androgen therapy can lead to fluid retention, which would typically cause weight gain rather than weight loss. Androgens promote anabolism and can increase muscle mass and erythrocyte production, but they also influence fluid balance by affecting renal sodium and water reabsorption.
Choice B rationale
Androgen therapy generally does not cause hypotension. In some cases, it may lead to a slight increase in blood pressure due to fluid retention and effects on the renin-angiotensin-aldosterone system. Hypotension is not a recognized common adverse effect of androgen therapy.
Choice C rationale
Androgen therapy does promote muscle hypertrophy due to its anabolic effects, increasing protein synthesis and muscle mass. However, this is generally a desired therapeutic effect, not an adverse effect requiring monitoring for cessation, especially when used for conditions like muscle wasting.
Choice D rationale
Androgens can cause fluid retention, leading to edema. This occurs due to their influence on mineralocorticoid receptors in the renal tubules, which promotes sodium and water reabsorption. Nurses should monitor for signs of fluid overload, such as peripheral or pulmonary edema, and changes in body weight.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["200"]
Explanation
Step 1 is to determine the total volume to be infused, which is 100 mL.
Step 2 is to determine the infusion time in hours. The infusion time is 30 min, which is 0.5 hours.
Step 3 is to calculate the infusion rate in mL/hr by dividing the total volume by the infusion time in hours: 100 mL ÷ 0.5 hr = 200 mL/hr. The nurse should set the IV infusion pump to deliver 200 mL/hr.
Correct Answer is B
Explanation
Choice A rationale
Dry mouth can be an anticholinergic effect of some medications or a symptom of dehydration, but it is not a direct, priority adverse effect associated with ketorolac, which is an NSAID. While uncomfortable, it does not indicate immediate life-threatening organ dysfunction.
Choice B rationale
Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthesis, which can lead to adverse renal effects. Prostaglandins play a crucial role in maintaining renal blood flow and glomerular filtration rate. Oliguria (urine output < 0.5 mL/kg/hr or < 400 mL/24 hr) indicates potential acute kidney injury, a serious and life-threatening complication that requires immediate reporting to the provider.
Choice C rationale
Nausea is a common gastrointestinal adverse effect of NSAIDs, including ketorolac, due to direct irritation of the gastric mucosa or central effects. While it can cause discomfort and impact client well-being, it is generally not a life-threatening symptom and does not take priority over signs of organ damage.
Choice D rationale
Altered taste, or dysgeusia, can be an idiosyncratic drug reaction but is not a common or priority adverse effect of ketorolac. While it can affect appetite and client satisfaction, it does not signify acute organ damage or a life-threatening condition requiring urgent intervention.
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