A nurse is caring for a client who has a fungal infection and is prescribed amphotericin. What adverse effects should the nurse monitor for in this client?

Nephrotoxicity

Ototoxicity

Hepatotoxicity

Thrombocytopenia.

Answer and Explanation

The Correct Answer is A

Amphotericin B is a drug used to treat fungal infections, but it can cause kidney damage and electrolyte imbalance as a common side effect. The nurse should monitor the client’s urine output, creatinine, potassium, and magnesium levels.

Choice B is wrong because Ototoxicity is wrong because amphotericin B does not affect the ears or hearing.

Ototoxicity is more common with aminoglycosides, another class of antibiotics.

Choice C is wrong because Hepatotoxicity is wrong because amphotericin B does not cause liver damage.

Hepatotoxicity is more common with azoles, another class of antifungals.

Choice D is wrong because Thrombocytopenia is wrong because amphotericin B does not cause low platelet count.

Thrombocytopenia is more common with heparin, an anticoagulant drug.

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Correct Answer is ["A","B","C"]

Explanation

These are examples ofnon-nucleoside reverse transcriptase inhibitors (NNRTIs), which bind to and inhibit viral reverse transcriptase enzyme that is essential for viral RNA synthesis.NNRTIs block reverse transcriptase by binding directly to the enzyme and prevent the completion of DNA synthesis.

Choice D is wrong because rilpivirine (Edurant) is also an NNRTI, but it does not bind to the same site as efavirenz, nevirapine and etravirine.

Therefore, it is not part of the same antiviral group.

Choice E is wrong because nucleotide reverse transcriptase inhibitors (NRTIs) are different from NNRTIs.

NRTIs are analogues of the natural deoxynucleotides that compete with them for incorporation into the viral DNA chain.However, NRTIs lack a 3′-hydroxyl group on the deoxyribose moiety, which results in chain termination.

NRTIs do not bind to reverse transcriptase enzyme directly like NNRTIs do.

A. Cyclosporine B. Warfarin C. Metformin D. Digoxin. E. “It binds to ergosterol and creates holes in the cell membrane."

Correct Answer is A

Explanation

Cyclosporine can interact with caspofungin and increase its plasma concentration and risk of liver toxicity.Cyclosporine is a drug used to prevent organ rejection or suppress the immune system.

Choice B is wrong because warfarin does not have a significant interaction with caspofungin.Warfarin is a blood thinner that prevents blood clots.

Choice C is wrong because metformin does not have a significant interaction with caspofungin.Metformin is a drug used to lower blood sugar levels in diabetes.

Choice D is wrong because digoxin does not have a significant interaction with caspofungin.Digoxin is a drug used to treat heart failure and irregular heartbeat.

Caspofungin is an antifungal drug that belongs to the echinocandin class.It works by inhibiting the synthesis of a component of the fungal cell wall called beta-glucan.

It is used to treat various fungal infections such as candidemia, esophageal candidiasis, invasive aspergillosis, and febrile neutropenia

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A nurse is caring for a client who has a fungal infection and is prescribed amphotericin. What adverse effects should the nurse monitor for in this client?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is caring for a client who has a viral infection. Which of the following antiviral groups bind to and inhibit viral reverse transcriptase enzyme that is essential for viral RNA synthesis? (Select all that apply)

Correct Answer is ["A","B","C"]

Explanation

A nurse is reviewing the medication history of a client who has a fungal infection and is prescribed caspofungin. The nurse should identify that which of the following medications can interact with caspofungin?

Correct Answer is A

Explanation

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A nurse is caring for a client who has a fungal infection and is prescribed amphotericin. What adverse effects should the nurse monitor for in this client?