A nurse is caring for a client who has a pulmonary embolism. The nurse should identify that the release of inflammatory mediators leads to which of the following pathologic findings?
Decreased pulmonary vascular resistance
Hypercapnia
Hypoventilation
Respiratory alkalosis
The Correct Answer is D
Correct answer: D
Choice A Reason:
Decreased pulmonary vascular resistance is incorrect. Inflammatory mediators released in response to a pulmonary embolism can lead to vasoconstriction and increased pulmonary vascular resistance. This is part of the body's response to redirect blood flow away from the affected area of the lung and maintain adequate perfusion to other areas.
Choice B Reason:
Hypercapnia is incorrect. Hypercapnia refers to elevated levels of carbon dioxide (CO2) in the blood. Hypocapnia usually is present with embolism; hypercapnia, on the other hand, is rare.
Choice C Reason:
Hypoventilation is incorrect. Hypoventilation occurs when there is inadequate ventilation of the lungs relative to metabolic demands. In the context of a pulmonary embolism, hypoventilation can occur due to factors such as pain, respiratory muscle fatigue, or impaired gas exchange, all of which can be influenced by the release of inflammatory mediators.
Choice D Reason:
Respiratory alkalosis is correct. In response to the blockage and the resulting inflammation, the body often increases the respiratory rate as a compensatory mechanism to maintain adequate oxygen levels and remove carbon dioxide. Due to the increased breathing rate, there is excessive exhalation of carbon dioxide, leading to a decrease in the partial pressure of CO2 in the blood. This results in an increase in blood pH, causing respiratory alkalosis.

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A.Osmotic edema refers to fluid shifts due to changes in osmotic gradients (as seen in conditions like hyponatremia), not the inflammatory process of meningitis.
B.While inflammation is a key part of the body's response in meningitis, the edema is not a result of generalized whole-body inflammation. The edema is more directly linked to local inflammatory reactions in the brain triggered by the pathogen’s by-products.
C.Bacterial cell walls, endotoxins, and other components released by the bacteria directly stimulate inflammation, causing the breakdown of the BBB and allowing fluid and inflammatory cells to leak into the brain tissue.
D.This description is more aligned with the pathophysiology of conditions like hydrocephalus rather than meningitis. In meningitis, cerebral edema is primarily due to the inflammatory response, not abnormal CSF flow.
Correct Answer is B
Explanation
Choice A Reason:
Flying itself is not typically considered a factor that worsens MS manifestations. However, factors related to flying, such as stress, fatigue, changes in routine, and potential exposure to infections, may contribute to symptom exacerbation in some individuals with MS.
Choice B Reason:
Sunbathing is appropriate. Exposure to excessive heat, such as sunbathing or prolonged exposure to hot weather, can lead to temporary worsening of MS symptoms, a phenomenon known as Uhthoff's phenomenon. Increased body temperature can temporarily impair nerve conduction in individuals with MS, resulting in exacerbation of symptoms such as fatigue, weakness, sensory disturbances, and cognitive impairment.
Choice C Reason:
Working in an office is inappropriate. Working in an office environment is not inherently associated with exacerbation of MS manifestations. However, factors such as stress, fatigue, poor ergonomic conditions, and limited mobility during prolonged periods of sitting may contribute to symptom exacerbation in some individuals with MS.
Choice D Reason:
High altitude travel is inappropriate. High altitude travel can exacerbate MS symptoms due to the decreased oxygen levels and potential changes in barometric pressure at high altitudes. Hypoxia (low oxygen levels) at high altitudes may exacerbate fatigue, weakness, and cognitive impairment in individuals with MS. Changes in barometric pressure can also trigger or worsen symptoms such as headaches, sensory disturbances, and balance problems in some individuals with MS.
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