A nurse is caring for a client who has a viral infection. Which of the following antiviral groups inhibits viral DNA polymerase or reverse transcriptase enzymes that are essential for viral DNA or RNA synthesis?
Nucleoside analogs
Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
Nucleotide reverse transcriptase inhibitors (NRTIs)
Protease inhibitors (PIs).
The Correct Answer is A
This is because nucleoside analogs inhibit viral DNA polymerase or reverse transcriptase enzymes that are essential for viral DNA or RNA synthesis.
Some possible explanations for the other choices are:
Choice B is wrong because Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are wrong because they do not inhibit viral DNA polymerase, but rather bind directly to reverse transcriptase and block its activity.
Choice C is wrong because Nucleotide reverse transcriptase inhibitors (NRTIs) are wrong because they are not nucleosides, but nucleotides that need to be phosphorylated before they can inhibit reverse transcriptase.
Choice D is wrong because Protease inhibitors (PIs) are wrong because they do not inhibit viral DNA polymerase or reverse transcriptase, but rather block the protease enzyme that cleaves viral proteins into functional units.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["C","D"]
Explanation
The nurse should instruct the client to avoid sexual intercourse until the infection is cleared, as it can cause irritation and inflammation of the vaginal mucosa and potentially transmit the infection to the partner.The nurse should also instruct the client to use a backup method of contraception if using oral contraceptives, as miconazole cream can reduce the effectiveness of hormonal contraceptives.
Choice A is wrong because the client should apply the cream twice a day for 7 days, not once a day.
Choice B is wrong because the client should not wash the applicator with soap and water after each use, as it can alter the pH of the vagina and promote fungal growth.
Choice E is wrong because bleeding or bruising are not common side effects of miconazole cream and are not related to vaginal candidiasis infection.
Correct Answer is A
Explanation
This is because nucleoside analogs inhibit viral DNA polymerase or reverse transcriptase enzymes that are essential for viral DNA or RNA synthesis.
Some possible explanations for the other choices are:
Choice B is wrong becauseNon-nucleoside reverse transcriptase inhibitors (NNRTIs) are wrong because they do not inhibit viral DNA polymerase, but rather bind directly to reverse transcriptase and block its activity.
Choice C is wrong becauseNucleotide reverse transcriptase inhibitors (NRTIs) are wrong because they are not nucleosides, but nucleotides that need to be phosphorylated before they can inhibit reverse transcriptase.
Choice D is wrong becauseProtease inhibitors (PIs) are wrong because they do not inhibit viral DNA polymerase or reverse transcriptase, but rather block the protease enzyme that cleaves viral proteins into functional units.
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