A nurse is caring for a client who has HIV-I infection and is prescribed zidovudine as part of antiretroviral therapy. The nurse should monitor the client for Which of the following adverse effects of this medication?
Renal failure
Metabolic alkalosis
Aplastic anemia
Cardiac dysrhythmia
The Correct Answer is C
Zidovudine (AZT) is an antiretroviral drug used in treatment of HIV to suppress viral replication. It causes aplastic anemia, suppression of the bone marrow, leasing to reduces production of all hematopoietic cell lines including red blood cells, white blood cells, and platelets.
A, B, and D - are not associated with Zidovudine use
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Related Questions
Correct Answer is B
Explanation
Severe nausea and vomiting can lead to respiratory acidosis due to the loss of gastric contents, which contain hydrochloric acid. When vomiting is prolonged or severe, the loss of acid can result in metabolic alkalosis.
A. Respiratory alkalosis occurs due to hyperventilation in conditions such as anxiety, salicylism
C. metabolic acidosis occurs in conditions where there is increased secretion of acid for example DKA
D. Respiratory acidosis occurs due to impaired ventilation such as chest trauma
Correct Answer is D
Explanation
The regular insulin should be administered subcutaneously about 30 mins before the client take their meals. This is because the insulin has a short onset of action. The peak time (30 mins after injection) should match the eating time provide optimum sugar control
B Arrival of the tray does not provide an exact time account to help match the peak time with meal time
C regular insulin should be given before meals
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