A nurse is caring for a client who has HIV-I infection and is prescribed zidovudine as part of antiretroviral therapy. The nurse should monitor the client for Which of the following adverse effects of this medication?
Renal failure
Metabolic alkalosis
Aplastic anemia
Cardiac dysrhythmia
The Correct Answer is C
Zidovudine (AZT) is an antiretroviral drug used in treatment of HIV to suppress viral replication. It causes aplastic anemia, suppression of the bone marrow, leasing to reduces production of all hematopoietic cell lines including red blood cells, white blood cells, and platelets.
A, B, and D - are not associated with Zidovudine use
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Amphotericin B causes renal injury and baseline renal function is an important predictor of risk of nephrotoxicity. A BUN of 55mg/mL indicates already compromised renal function and hence requires follow up due to risk of further damage.
A. Sodium level within the normal range (140 mEq/L) is a contraindication for initiating amphotericin B therapy.
C. Amphotericin B causes hypokalemia buy potassium level of 4.5 is within the normal range.
D. Glucose level within the normal range (120 mg/dL) is not a contraindication for initiating amphotericin B therapy.
Correct Answer is C
Explanation
Rationale- Live attenuated influenza vaccine is a weakened form of the influenza virus that promotes production of antibodies in the host to fight infections in case of exposure to influenza virus. The virus is contraindicated in individuals with weak immune system such as those above 50 years old due to risk of causing severe infection.
A-History of MI is not an immunocompromised state
B-History of cigarette smoking predisposes to influenza infection but is not a contraindication to LAV D-History of travel to Europe could expose have exposed the client to influenza but that is not a
contraindication to LAV
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