A nurse is caring for a client who is prescribed warfarin therapy for an artificial heart valve. Which of the following laboratory values should the nurse monitor for a therapeutic effect of warfarin?
Activated partial thromboplastin time (APTT)
Bleeding time
Prothrombin time (PT)
Hemoglobin (Hgb)
The Correct Answer is C
warfarin inhibits vitamin K epoxide reductase interfering with the synthesis of vitamin K dependent clotting factors (II, VII, IX, and X). This prolongs the prothrombin time, expressed in the form of INR international normalized ratio. Monitoring of INR helps to ensure that the prescribed dosages are within the therapeutic levels without increasing the risk of bleeding. The target INR range is between 2.5 and 3.5.
A. Used to monitor heparin therapy
B, D- not used for monitoring
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Rationale- Levothyroxine is a synthetic form of thyroxine. It is used to provide the body with thyroxine to sustain basal metabolism in cases of hypothyroidism. An overdose of the medication causes symptoms which include insomnia, hyperactive tendon reflexes, diarrhea and anxiety
A, B, D- features of hypothyroidism
Correct Answer is B
Explanation
Spironolactone is a potassium-sparing diuretic used in the management of ascites associated with liver failure. Its mechanism of action includes blocking the actions of aldosterone, a hormone that promotes sodium retention and potassium excretion in the kidneys. This results in increased urinary sodium excretion and hyponatremia and hyperkalemia.
A. Decreased chloride level is not typically associated with spironolactone use.
C. Spironolactone is a potassium-sparing diuretic, so it leads to an increased potassium level (hyperkalemia)
D. Spironolactone is not associated with decreased phosphate levels.
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