A nurse is caring for a client who is prescribed warfarin therapy for an artificial heart valve. Which of the following laboratory values should the nurse monitor for a therapeutic effect of warfarin?
Activated partial thromboplastin time (APTT)
Bleeding time
Prothrombin time (PT)
Hemoglobin (Hgb)
The Correct Answer is C
warfarin inhibits vitamin K epoxide reductase interfering with the synthesis of vitamin K dependent clotting factors (II, VII, IX, and X). This prolongs the prothrombin time, expressed in the form of INR international normalized ratio. Monitoring of INR helps to ensure that the prescribed dosages are within the therapeutic levels without increasing the risk of bleeding. The target INR range is between 2.5 and 3.5.
A. Used to monitor heparin therapy
B, D- not used for monitoring
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Correct Answer is C
Explanation
Ondansetron is an antiemetic used in the prevention and management of nausea and vomiting. Its potential side effects include headaches.
A, B, D- Photosensitivity, polyuria and dependent edema are not adverse effects of ondansetron.
Correct Answer is C
Explanation
Zidovudine (AZT) is an antiretroviral drug used in treatment of HIV to suppress viral replication. It causes aplastic anemia, suppression of the bone marrow, leasing to reduces production of all hematopoietic cell lines including red blood cells, white blood cells, and platelets.
A, B, and D - are not associated with Zidovudine use
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