A nurse is caring for a client who is prescribed warfarin therapy for an artificial heart valve. Which of the following laboratory values should the nurse monitor for a therapeutic effect of warfarin?

Activated partial thromboplastin time (APTT)

Bleeding time

Prothrombin time (PT)

Hemoglobin (Hgb)

Answer and Explanation

The Correct Answer is C

warfarin inhibits vitamin K epoxide reductase interfering with the synthesis of vitamin K dependent clotting factors (II, VII, IX, and X). This prolongs the prothrombin time, expressed in the form of INR international normalized ratio. Monitoring of INR helps to ensure that the prescribed dosages are within the therapeutic levels without increasing the risk of bleeding. The target INR range is between 2.5 and 3.5.
A. Used to monitor heparin therapy

B, D- not used for monitoring

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Correct Answer is C

Explanation

Mydriatic eye drops are used in ophthalmology to dilate the pupil for visualization of the retina and the vitreous humor. Absorption into the system an lead to systemic anticholinergic effect such a s constipation due to reduce gastrointestinal motility.

A. Bradycardia is a cholinergic effect

B and D are not typical anticholinergic effects

A. A client received crushed bupropion XL tablet mixed with applesauce. B. A nurse injected Demerol 1M into the vastus lateralis site of adult. C. A nurse used a 25-gauge inch needle to administer heparin injection. D. A client received gentamicin intermittent IV bolus over I hr.

Correct Answer is A

Explanation

Bupropion XL tablets should be taken whole. Crushing the tablet interferes with the pharmacokinetics of the drug leading to reduced efficacy and increased risk of toxicity. Administering bupropion XL inappropriately could result in harm to the client and should prompt the nurse to file an incident report to document the error and ensure appropriate follow-up and monitoring.

B. Meperidine is a commonly administered opioid analgesic and can be given intramuscularly in appropriate doses and sites.

C. Selection of the needle length and gauge depend on the route of administration and individual client's characteristics

D.Gentamicin can be administered by intermittent IV bolus over a prolonged period as part of its dosing regimen.

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A nurse is caring for a client who is prescribed warfarin therapy for an artificial heart valve. Which of the following laboratory values should the nurse monitor for a therapeutic effect of warfarin?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is caring for a client who is receiving mydriatic eye drops. Which of the following manifestations indicates to the nurse that the client has developed a systemic anticholinergic effect?

Correct Answer is C

Explanation

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Correct Answer is A

Explanation

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