A nurse is caring for a client with a new diagnosis of hypertension.
Which of the following medications is used to treat hypertension? (Select All That Apply.)

Choice A rationale

Celecoxib does not inhibit the histamine response. Histamine is involved in allergic reactions, and celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that targets specific enzymes involved in inflammation.

Choice B rationale

Celecoxib specifically inhibits COX-2, an enzyme involved in the inflammation pathway. This selective inhibition helps reduce inflammation and pain without significantly affecting COX-1, which is protective for the stomach lining.

Choice C rationale

COX-1 is not the primary target of celecoxib. Inhibition of COX-1 can lead to gastrointestinal side effects, which celecoxib aims to minimize by selectively inhibiting COX-2 instead.

Choice D rationale

Celecoxib does not inhibit beta receptors. Beta receptors are involved in cardiovascular responses, and beta blockers are used for conditions like hypertension, not inflammation.

Choice A rationale

Dextromethorphan is not used for asthma. Asthma treatment typically involves bronchodilators and anti-inflammatory medications.

Choice B rationale

Dextromethorphan is an antitussive used to suppress coughing. It acts on the cough center in the brain to reduce the urge to cough.

Choice C rationale

This medication is not used for pain reduction. Pain management usually involves analgesics or anti-inflammatory drugs.

Choice D rationale

Dextromethorphan is not indicated for allergic rhinitis. Allergic rhinitis treatments typically include antihistamines or nasal corticosteroids.