The nurse is caring for a patient receiving vancomycin (Vancocin) for treatment of an infection caused by methicillin-resistant Staphylococcus aureus (MRSA).
Which assessment finding would indicate a potentially serious adverse reaction to this drug?
Redness and itching at the infusion site
Flushing, rash, and pruritus on the face and upper torso
Nausea, vomiting, and abdominal cramps
Tinnitus, vertigo, and hearing loss.
Report any signs of oral thrush to the provider.
The Correct Answer is D
These are signs of ototoxicity, a potentially serious adverse reaction to vancomycin (Vancocin) and other aminoglycosides. Ototoxicity can damage the inner ear and cause permanent hearing loss or balance problems.
Choice A is wrong because redness and itching at the infusion site are not specific to vancomycin (Vancocin) and could indicate a local irritation or an allergic reaction to any drug.
Choice B is wrong because flushing, rash, and pruritus on the face and upper torso are symptoms of red man syndrome, a common but not serious side effect of vancomycin (Vancocin) that occurs due to rapid infusion and histamine release. Red man syndrome can be prevented by infusing the drug over at least 1 hour.
Choice C is wrong because nausea, vomiting, and abdominal cramps are not specific to vancomycin (Vancocin) and could be caused by many factors, such as infection, food poisoning, or other drugs.
Normal ranges for vancomycin (Vancocin) trough levels are 10 to 20 mcg/mL for most infections and 15 to 20 mcg/mL for serious infections such as osteomyelitis, endocarditis, or meningitis. Levels above 20 mcg/mL increase the risk of ototoxicity and nephrotoxicity.
Therefore, the nurse should monitor the patient’s trough levels regularly and report any abnormal findings to the prescriber.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
They are effective against a few types of organisms.Narrow spectrum antibiotics are antibiotics that work against a limited range of bacteria, usually either gram-positive or gram-negative.They are more specific and less likely to cause resistance or disrupt the normal flora.
Choice A) They are effective against gram-positive bacteria only.This is not true because some narrow spectrum antibiotics can also target gram-negative bacteria, such as aminoglycosides.
Choice B) They are effective against gram-negative bacteria only.This is not true because some narrow spectrum antibiotics can also target gram-positive bacteria, such as vancomycin.
Choice C) They are effective against one type of organism.This is too restrictive because narrow spectrum antibiotics can work against more than one type of organism, such as penicillins that target both streptococci and staphylococci.
Correct Answer is B
Explanation
This is because antibiotics act synergistically with the immune system to subdue infection, and it is critical for success that the host defenses are adequate.
Choice A is wrong becauseAge is wrong because age is a general factor that must be considered when choosing any medication, not just antimicrobials.
Choice C is wrong becauseGenetic heritage is wrong because genetic heritage is also a general factor that may affect the metabolism and excretion of medications, not the selection of antimicrobials.
Choice D is wrong becausePrevious medication reactions is wrong because previous medication reactions are also a general factor that may indicate allergies or intolerances to certain medications, not the selection of antimicrobials.
Normal ranges for immune function vary depending on the type and level of immunity measured, such as innate, adaptive, humoral or cellular immunity.Some common tests for immune function include complete blood count (CBC), immunoglobulin levels, complement levels, antibody titers and skin tests.
Normal ranges for these tests depend on the laboratory and the method used, but some examples are:
• CBC: white blood cell count 4.5-11 x 10^9/L; neutrophils 40-75%; lymphocytes 20-50%; monocytes 2-10%; eosinophils 1-6%; basophils 0-2%.
• Immunoglobulin levels: IgG 7-16 g/L; IgA 0.7-4 g/L; IgM 0.4-2.3 g/L; IgE 0-0.4 g/L.
• Complement levels: C3 0.9-1.8 g
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