Which antibiotics are classified as concentration-dependent antimicrobials?
Ciprofloxacin
Imipenem
Penicillin V
Metronidazole
Gentamicin.
The Correct Answer is E
Gentamicin is an example of a concentration-dependent antimicrobial, which means that it achieves increasing bacterial kill with increasing levels of drug. The peak concentration and the area under the concentration curve (AUC) determine the efficacy of these antibiotics. Other examples of concentration-dependent antimicrobials include fluoroquinolones, daptomycin, aminoglycosides, and amphotericin
Choice A is wrong because ciprofloxacin is a fluoroquinolone, which is also a concentration-dependent antimicrobial.
Choice B is wrong because imipenem is a carbapenem, which is a type of beta-lactam antibiotic. Beta-lactams are time-dependent antimicrobials, which means that their bactericidal activity depends on the duration of the effective concentration.
Choice C is wrong because penicillin V is another type of beta-lactam antibiotic, which is also a time-dependent antimicrobial.
Choice D is wrong because metronidazole is a bactericidal agent that has both time- and concentration-dependent properties. However, it is not classified as a concentration-dependent antimicrobial according to the AMEG categorization of antibiotics in the European Union.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","C","D"]
Explanation
The nurse should include these instructions in the teaching because:
• Tetracycline should be taken on an empty stomach to avoid interference with absorption.
• Dairy products should be avoided while taking this drug because they contain calcium, which can form insoluble complexes with tetracycline and reduce its effectiveness.
• Sunscreen or sun avoidance should be used while taking this drug because it can cause photosensitivity, which increases the risk of sunburn and skin damage.
• Plenty of fluids should be drunk while taking this drug because it can cause nephrotoxicity, which is damage to the kidneys.
Choice E is wrong because vaginal itching or discharge is not a common side effect of tetracycline.It may indicate a superinfection, which is a secondary infection caused by the disruption of normal flora by antibiotics.
This should be reported to the health care provider as soon as possible.
Correct Answer is ["A","B","C"]
Explanation
Oxacillin, erythromycin and clindamycin are all antibiotics that are sensitive to Staphylococcus aureus according to the culture and sensitivity report.
This means that they can inhibit or kill the bacteria that are causing the wound infection.These antibiotics belong to different classes of drugs that have different mechanisms of action and spectrum of activity.
Choice D and E are wrong because vancomycin and linezolid are antibiotics that are usually reserved for more resistant strains of Staphylococcus aureus, such as methicillin-resistant Staphylococcus aureus (MRSA) or
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