A nurse is preparing to administer 1,000 mL of lactated Ringer's IV over 6 hr. The drop factor of the manual IV tubing is 10 gtt/mL. The nurse should set the manual IV infusion to deliver how many gtt/min? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

A) H2-receptor blockers:
H2-receptor blockers, such as ranitidine and famotidine, are commonly used to reduce stomach acid production and treat peptic ulcer disease. They help promote ulcer healing and alleviate symptoms. These medications are generally safe and appropriate for use in clients with peptic ulcer disease.

B) Antacids:
Antacids are medications that neutralize stomach acid and provide symptomatic relief from peptic ulcer disease. While they do not directly treat the underlying cause of the ulcer, they can help alleviate symptoms such as pain and discomfort. Antacids are generally safe for use in clients with peptic ulcer disease.

C) PPIs (Proton Pump Inhibitors):
PPIs, such as omeprazole and pantoprazole, are potent acid-suppressing medications commonly used to treat peptic ulcer disease and gastroesophageal reflux disease (GERD). They are effective at reducing stomach acid production and promoting ulcer healing. PPIs are generally safe and appropriate for use in clients with peptic ulcer disease.

D) NSAIDs (Nonsteroidal Anti-Inflammatory Drugs).
NSAIDs, such as ibuprofen, aspirin, and naproxen, can exacerbate peptic ulcer disease by increasing the risk of gastric irritation, erosion, and ulceration. These medications inhibit the production of prostaglandins, which help protect the stomach lining. Chronic or excessive use of NSAIDs can lead to the development of new ulcers or worsening of existing ulcers. Therefore, clients with peptic ulcer disease are typically advised to avoid NSAIDs or to use them with caution under the guidance of a healthcare provider.

A) Low-back pain:
Low-back pain is not typically associated with transfusion reactions. While certain complications of blood transfusions, such as transfusion-related acute lung injury (TRALI) or hemolytic reactions, can cause back pain, diphenhydramine is not specifically administered to prevent this manifestation.

B) Fever:
Fever can be a manifestation of various transfusion reactions, including febrile non-hemolytic reactions or bacterial contamination of blood products. However, diphenhydramine is not typically administered to prevent fever associated with transfusion reactions. Instead, measures such as leukoreduction of blood products or premedication with acetaminophen may be used to reduce the risk of febrile reactions.

C) Dyspnea:
Dyspnea, or difficulty breathing, can occur in severe transfusion reactions such as transfusion-related acute lung injury (TRALI) or anaphylaxis. While diphenhydramine may be part of the treatment for anaphylaxis, it is not specifically administered to prevent dyspnea associated with transfusion reactions.

D) Urticaria.
Urticaria, commonly known as hives, is a common manifestation of an allergic transfusion reaction. Diphenhydramine is an antihistamine medication that can help prevent or alleviate allergic reactions, including urticaria, by blocking the action of histamine, a substance released during allergic reactions. Administering diphenhydramine before a blood transfusion is a preventive measure to reduce the risk of allergic transfusion reactions, including urticaria.