A nurse is preparing to administer 1,000 mL of lactated Ringer's IV over 6 hr. The drop factor of the manual IV tubing is 10 gtt/mL. The nurse should set the manual IV infusion to deliver how many gtt/min? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

A. Hypotension: Norepinephrine is administered to treat hypotension, so monitoring for hypotension is not typically a concern while the patient is receiving this medication. In fact, hypotension is often the reason for administering norepinephrine in the first place.

B. Liver failure: Monitoring for signs of liver failure may be important in patients receiving certain medications, but it is not a specific consideration when administering norepinephrine. Norepinephrine primarily affects blood pressure regulation and does not typically have direct effects on liver function.

C. Bradycardia: While norepinephrine can increase blood pressure by constricting blood vessels, it may also cause reflex bradycardia (a decrease in heart rate) as a compensatory response. However, the primary concern with norepinephrine administration is hypertension, not bradycardia.

D. Hypertension
Norepinephrine (Levophed) is a vasopressor medication commonly used to treat hypotension and shock. It works by constricting blood vessels, which increases blood pressure. Therefore, when administering norepinephrine, the nurse should monitor the patient for hypertension, as the medication's intended effect is to raise blood pressure.

A) A client who has a kidney stone:
Misoprostol is not contraindicated in clients who have kidney stones. Kidney stones are not a known contraindication for the use of misoprostol.

B) A client who is pregnant.
Misoprostol is a medication commonly used to prevent gastric ulcers in individuals who are taking nonsteroidal anti-inflammatory drugs (NSAIDs) for conditions such as osteoarthritis. However, it is contraindicated in pregnant women due to its potential to cause uterine contractions, leading to miscarriage or preterm labor. Misoprostol is classified as a pregnancy category X medication, meaning that there is clear evidence of fetal risk based on human or animal studies, and its use is contraindicated during pregnancy.

C) A client who has a urinary tract infection:
Misoprostol is not contraindicated in clients who have urinary tract infections. Urinary tract infections are not a known contraindication for the use of misoprostol.

D) A client who has osteoarthritis:
Misoprostol is commonly used in clients with conditions such as osteoarthritis to prevent NSAID-induced gastric ulcers. Osteoarthritis is not a contraindication for the use of misoprostol when indicated for gastric ulcer prevention in individuals taking NSAIDs.