A nurse is preparing to administer an aminoglycoside to a client.
The nurse would be alert for the development of which of the following toxicities?
Nephrotoxicity.
Cardiotoxicity.
Hepatotoxicity.
Cytotoxicity.
The Correct Answer is A
Choice A rationale:
Aminoglycosides are known to have nephrotoxic effects. Nephrotoxicity refers to kidney toxicity, and aminoglycosides can cause damage to the renal tubules, leading to impaired kidney function. The nurse should be alert to this potential toxicity when administering these drugs, as it can result in kidney dysfunction, altered serum creatinine levels, and electrolyte imbalances.
Choice B rationale:
Cardiotoxicity is not typically associated with aminoglycosides. These antibiotics primarily affect the kidneys and the inner ear. There is no direct relationship between aminoglycosides and cardiac toxicity.
Choice C rationale:
Hepatotoxicity refers to liver toxicity and is not a common side effect of aminoglycosides. Aminoglycosides are primarily metabolized in the kidneys and are excreted through urine, making kidney toxicity a more significant concern.
Choice D rationale:
Cytotoxicity is a broad term that refers to the toxicity of cells. Aminoglycosides do not typically cause generalized cytotoxic effects in the body. Their primary toxicities are related to specific organ systems, such as the kidneys and the inner ear.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale:
Hemolytic anemia Hemolytic anemia is a contraindication for the use of ferrous sulfate, which is an iron supplement. Iron can exacerbate hemolysis in individuals with certain types of hemolytic anemia, leading to further breakdown of red blood cells. Therefore, the nurse should withhold the drug and consult with the primary healthcare provider to explore alternative treatments.
Choice B rationale:
Vitamin B12 deficiency anemia Vitamin B12 deficiency anemia is not a direct contraindication for ferrous sulfate. Ferrous sulfate is used to treat iron-deficiency anemia, and vitamin B12 deficiency anemia is a separate condition that requires different treatments. These two conditions are not typically interrelated in terms of treatment.
Choice C rationale:
Anemia of chronic kidney disease Anemia of chronic kidney disease is a condition where the kidneys are unable to produce enough erythropoietin, a hormone that stimulates red blood cell production. While ferrous sulfate may not be the first-line treatment for this type of anemia, it is not a strict contraindication. The decision to use iron supplements would depend on the individual patient's needs and the primary healthcare provider's recommendations.
Choice D rationale:
Hypertension Hypertension is not a contraindication for ferrous sulfate use. While patients with high blood pressure should be monitored closely, iron supplementation does not directly affect blood pressure regulation. The nurse should consider potential interactions with other medications the client may be taking, but hypertension alone is not a reason to withhold ferrous sulfate.
Correct Answer is A
Explanation
Choice A rationale:
Constipation is a potential adverse reaction to ferrous sulfate (Feosol), an iron supplement. Iron can cause gastrointestinal disturbances, including constipation, due to its effect on slowing down bowel movements and hardening of stool. It is important for the nurse to discuss this with the client before administering the drug to ensure the client is aware of this potential side effect.
Choice B rationale:
Fluid retention is not a common adverse reaction to ferrous sulfate. In fact, iron supplements are more likely to cause gastrointestinal issues like constipation rather than fluid retention.
Choice C rationale:
Fatigue is not a direct adverse reaction to ferrous sulfate. In some cases, iron deficiency can lead to fatigue, but this is usually a result of the underlying condition and not the medication itself.
Choice D rationale:
Clay-colored stools are not a typical adverse reaction to ferrous sulfate. This may indicate a potential issue with liver function or biliary obstruction but is not directly related to the iron supplement.
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