A client is receiving antiretroviral therapy.
Which adverse reactions would the nurse include in the teaching plan for this client?

Sedation.

Bruising.

Altered taste.

Constipation.

Answer and Explanation

The Correct Answer is B

Choice A rationale:

Sedation is not a common adverse reaction to antiretroviral therapy. Antiretroviral medications are primarily used to treat HIV and do not typically cause sedation.

Choice B rationale:

Bruising is a potential adverse reaction to antiretroviral therapy. Some antiretroviral medications can cause blood-related side effects, such as decreased platelet count, which can result in easy bruising and bleeding. It's important for the nurse to include this in the teaching plan to ensure the client is aware of this potential side effect.

Choice C rationale:

Altered taste is not a common adverse reaction to antiretroviral therapy. While some medications can cause taste disturbances, this is not a typical side effect of antiretroviral drugs.

Choice D rationale:

Constipation is not a common adverse reaction to antiretroviral therapy. Antiretroviral medications primarily target the HIV virus and do not typically cause gastrointestinal issues like constipation.

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Correct Answer is B

Explanation

Choice A rationale:

Alkylating agents. Alkylating agents are not cell cycle-specific. These agents work by directly binding to DNA and interfering with the cell's ability to replicate and divide. Their action is not limited to a specific phase of the cell cycle, making them non-cell cycle-specific agents. Alkylating agents are often used in cancer chemotherapy to prevent cell division and growth.

Choice C rationale:

Antineoplastic antibiotics. Antineoplastic antibiotics are not cell cycle-specific either. These drugs, such as doxorubicin and bleomycin, work by disrupting DNA and RNA synthesis and are used to treat various types of cancer. However, they do not specifically target cells in a particular phase of the cell cycle.

Choice D rationale:

Retinoids. Retinoids are not cell cycle-specific antineoplastic agents. Retinoids are compounds related to vitamin A and are used for various medical purposes, including some cancer treatments. However, their mechanism of action is not tied to a specific phase of the cell cycle, making them non-cell cycle-specific.

Choice B rationale:

Plant alkaloids. Plant alkaloids, such as vinca alkaloids (vincristine and vinblastine) and taxanes (paclitaxel), are considered cell cycle-specific antineoplastic drugs. These agents interfere with microtubule function, which is critical during mitosis (cell division). By disrupting microtubules, they specifically target rapidly dividing cancer cells during the M phase of the cell cycle. This selectivity for actively dividing cells makes plant alkaloids cell cycle-specific antineoplastic drugs.

A. Alkylating agents. B. Plant alkaloids. C. Antineoplastic antibiotics. D. Retinoids.

Correct Answer is A

Explanation

Choice A rationale:

Alkylating agents are cell cycle-specific drugs. They work on cells during various stages of the cell cycle and are classified as cell cycle phase-nonspecific drugs. These drugs form covalent bonds with DNA, preventing DNA replication and transcription. This action disrupts the cell cycle, making them effective against actively dividing cells.

Choice B rationale:

Plant alkaloids are not cell cycle-specific drugs. Plant alkaloids, such as vinblastine and vincristine, are derived from plants and are classified as cell cycle phase-specific drugs. They primarily affect cells during the M phase of the cell cycle by disrupting microtubule formation. While they are effective against rapidly dividing cells, they are not cell cycle-specific.

Choice C rationale:

Antineoplastic antibiotics are not cell cycle-specific drugs. These drugs, such as doxorubicin and daunorubicin, are used in cancer treatment and primarily work by intercalating with DNA and inhibiting topoisomerase enzymes. Their mechanisms of action do not specifically target a particular phase of the cell cycle, making them cell cycle phase-nonspecific.

Choice D rationale:

Retinoids are not cell cycle-specific drugs. Retinoids are derived from vitamin A and have various mechanisms of action, including regulating cell growth and differentiation. They are not classified as cell cycle-specific drugs.

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A client is receiving antiretroviral therapy.Which adverse reactions would the nurse include in the teaching plan for this client?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A group of nursing students are reviewing antineoplastic drugs.The students demonstrate understanding of the information when they identify which of the following as cell cycle specific?

Correct Answer is B

Explanation

A group of nursing students are reviewing antineoplastic drugs.The students demonstrate understanding of the information when they identify which of the following as cell cycle specific?

Correct Answer is A

Explanation

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A client receiving which of the following medications would the nurse identify as being at increased risk for candidal infections?

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A client is receiving antiretroviral therapy.
Which adverse reactions would the nurse include in the teaching plan for this client?