A nurse is preparing to administer an amphotericin B lipid complex via intermittent IV bolus to a client who has infective endocarditis. Which of the following actions should the nurse take?
Use a gravity flow set.
Discard the medication if it is yellow.
Prime the tubing with 0.9% sodium chloride.
Administer the medication over 2 hr.
The Correct Answer is C
A. Use a gravity flow set:
Incorrect Explanation: Using a gravity flow set is not appropriate for administering amphotericin B lipid complex.
Explanation: Amphotericin B lipid complex is typically administered using a dedicated infusion pump to ensure accurate control over the infusion rate and to prevent potential complications.
B. Discard the medication if it is yellow:
Incorrect Explanation: Discarding the medication solely based on its color may not be accurate for the amphotericin B lipid complex.
Explanation: Amphotericin B lipid complex may appear yellowish, and the color itself is not necessarily an indication of its potency or stability. It's important to follow specific guidelines provided by the pharmacy or manufacturer for assessing the integrity of the medication.
C. Prime the tubing with 0.9% sodium chloride:
Correct Answer: Priming the tubing with 0.9% sodium chloride is the appropriate action to ensure the medication is properly administered.
Explanation: Priming the tubing with a compatible solution, such as 0.9% sodium chloride, helps prevent the medication from adhering to the tubing and ensures that the full dose reaches the client.
D. Administer the medication over 2 hr:
Incorrect Explanation: Administering amphotericin B lipid complex over 2 hours is not the standard infusion time.
Explanation: Amphotericin B lipid complex is typically administered over a longer period, often 2-6 hours. However, the specific infusion rate and duration may vary based on the client's condition and the healthcare provider's orders.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Hct 43%
Explanation: Hematocrit (Hct) measures the proportion of blood volume that is occupied by red blood cells. A low Hct level could indicate anemia, which might affect the body's ability to deliver sufficient oxygen to tissues.
B. Creatinine 2.5 mg/dL
Explanation: Elevated creatinine levels indicate potential kidney dysfunction. Tobramycin is primarily excreted by the kidneys, so elevated creatinine levels can increase the risk of tobramycin toxicity due to reduced drug clearance.
C. Sodium 137 mEq/L
Explanation: Sodium level within the normal range. It doesn't directly impact the administration of tobramycin.
D. Hgb 15 g/dL
Explanation: Hemoglobin (Hgb) measures the concentration of oxygen-carrying protein in the blood. A normal hemoglobin level is not directly related to the administration of tobramycin.

Correct Answer is D
Explanation
A. Increased blood pressure:
An elevated aPTT (activated partial thromboplastin time) suggests that the client is receiving heparin therapy. Heparin is an anticoagulant that prevents blood clotting. It's not likely to cause a significant increase in blood pressure directly. Changes in blood pressure may occur due to other factors, but they are not directly related to heparin therapy.
B. Decreased temperature:
Heparin administration does not typically have a direct effect on body temperature. Changes in body temperature might be due to other factors such as infection, but they are not a primary consideration when assessing the effects of heparin therapy.
C. Decreased respiratory rate:
Heparin administration is not known to directly affect respiratory rate. Changes in respiratory rate could be related to respiratory conditions, pain, or other factors unrelated to heparin therapy.
D. Increased pulse rate:
This is the correct choice. Heparin is known to affect the clotting process by inhibiting clot formation. An extended aPTT of 90 seconds indicates that the client's blood is taking longer to form clots than the normal range. This could lead to concerns about potential bleeding complications. Increased pulse rate could be an early sign of bleeding or decreased perfusion, as the body may attempt to compensate for reduced blood volume due to prolonged clotting times.

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