A nurse is providing education to a client recently diagnosed with chronic lymphocytic leukemia (CLL). The client asks, "How does CLL differ from other types of leukemia?" How should the nurse respond?
"CLL involves the overproduction of abnormal myeloid cells, while other types of leukemia affect lymphocytes."
"Unlike other leukemias, CLL has a rapid onset and aggressive course of disease progression."
"In CLL, abnormal lymphocytes accumulate and interfere with the production of other blood cells in the bone marrow."
"CLL is characterized by a genetic mutation in the bone marrow that leads to uncontrolled growth of red blood cells."
The Correct Answer is C
A) This choice is incorrect because CLL specifically involves the overproduction of abnormal lymphocytes, not myeloid cells. Myeloid cells are affected in other types of leukemia, such as AML.
B) This choice is incorrect because CLL is a chronic and indolent type of leukemia. It has a slow onset and progresses slowly over time, unlike some other leukemias that may have a more rapid course.
C) This choice is correct. In CLL, abnormal lymphocytes, mainly B-lymphocytes, accumulate in the bone marrow and interfere with the production of other blood cells, including red blood cells, platelets, and other white blood cells.
D) This choice is incorrect because CLL does not involve a genetic mutation leading to uncontrolled growth of red blood cells. That description is more characteristic of polycythemia vera, a different type of blood disorder.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A) This choice is incorrect because leukemia is not always caused by inherited genetic mutations. While genetic factors can contribute to the development of some types of leukemia, it is not the only cause.
B) This choice is incorrect because there are known genetic links to certain types of leukemia. For example, some forms of leukemia, such as chronic myeloid leukemia (CML), are associated with specific genetic mutations.
C) This choice is incorrect because genetic factors and environmental factors can both play a role in the development of leukemia. Some cases may be influenced more by genetic factors, while others may be influenced more by environmental factors.
D) This choice is correct. Leukemia can have various causes, including genetic mutations, exposure to certain environmental factors (e.g., radiation, certain chemicals), and viral infections. While some cases may have a genetic basis, others may be triggered by environmental factors or have an unknown cause.
Correct Answer is D
Explanation
A) This choice is incorrect because a history of frequent dental cavities is not a known risk factor for leukemia.
B) This choice is incorrect because allergies to pollen and pet dander are not associated with an increased risk of leukemia.
C) This choice is incorrect because recurrent urinary tract infections are not known to be a risk factor for leukemia.
D) This choice is correct. Previous treatment with chemotherapy and radiation is a significant risk factor for developing leukemia. Certain chemotherapeutic agents and radiation therapy can damage healthy blood-forming cells in the bone marrow, potentially leading to the development of leukemia later on. This type of leukemia is often referred to as secondary or treatment-related leukemia.
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