A nurse is reviewing the laboratory data of a client who is receiving filgrastim. Which of the following laboratory values should the nurse monitor to evaluate the effectiveness of the treatment?
INR
BUN
WBC count
Potassium level
The Correct Answer is C
Choice A Reason:
INR (International Normalized Ratio) is incorrect. INR is a measurement used to monitor the effects of anticoagulants like warfarin. It assesses the blood's ability to clot. Filgrastim does not directly affect INR levels, so monitoring INR would not provide information about the effectiveness of filgrastim in stimulating white blood cell production.
Choice B Reason:
BUN (Blood Urea Nitrogen) is incorrect. BUN levels primarily indicate kidney function and hydration status. They are not directly influenced by filgrastim treatment. Monitoring BUN is essential for assessing kidney function but does not reflect the effectiveness of filgrastim therapy in increasing white blood cell counts.
Choice C Reason:
WBC count is correct. Filgrastim is a medication that stimulates the production of white blood cells (WBCs), particularly neutrophils. Therefore, the key laboratory value to monitor for assessing the effectiveness of filgrastim therapy is the WBC count. An increase in the WBC count, particularly in the neutrophil count, signifies the intended therapeutic effect of filgrastim in boosting the immune system's response by increasing the production of these infection-fighting cells.
Choice D Reason:
Potassium level is incorrect. Potassium levels are crucial for heart and muscle function. While certain medications might affect potassium levels, filgrastim's primary action is on stimulating white blood cell production and does not directly impact potassium levels. Monitoring potassium levels is essential for overall health but does not specifically indicate the effectiveness of filgrastim treatment.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A Reason:
Dry cough is incorrect. While cough can be a side effect of amphotericin B, it's not a hallmark sign of an acute infusion reaction.
Choice B Reason:
Fever is correct. Acute infusion reactions to amphotericin B can manifest in various ways, and fever is a common sign indicating an immediate adverse reaction during the infusion. Other potential signs of an acute infusion reaction may include chills, rigors, hypotension, flushing, headache, or nausea.
Choice C Reason:
Pedal edema is incorrect. Swelling of the feet or pedal edema is not a typical manifestation of an acute infusion reaction to amphotericin B.
Choice D Reason:
Hyperglycemia is incorrect. Increased blood glucose levels (hyperglycemia) are not commonly associated with an acute infusion reaction to amphotericin B. However, amphotericin B may have effects on electrolytes and kidney function that could indirectly impact glucose levels.
Correct Answer is B
Explanation
Choice A Reason:
Tinnitus, a perception of noise or ringing in the ears, is not typically associated with paroxetine use.
Choice B Reason:
Drowsiness or somnolence is a common adverse effect associated with paroxetine and many other selective serotonin reuptake inhibitors (SSRIs). It's crucial for clients to be aware of this potential side effect, especially when starting the medication or adjusting the dosage. It might affect their ability to perform tasks requiring alertness, such as driving or operating machinery.
Choice C Reason:
Peripheral edema, or swelling in the extremities, is not a common adverse effect linked specifically to paroxetine use.
Choice D Reason:
Alopecia is correct. Alopecia, or hair loss, is not a commonly reported adverse effect of paroxetine.
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