A nurse is teaching a group of women about medications. The women want to know why so many drugs have unpredictable effects in women. The nurse will tell them that:
Drugs usually have more toxic effects in women.
Women metabolize drugs more slowly.
Most known drug effects are based on drug trials in men.
Women have varying responses to drugs during menstrual cycles.
The Correct Answer is C
Choice A Reason:
While it is true that women often experience more adverse drug reactions than men, this is not because drugs inherently have more toxic effects in women. The higher incidence of side effects in women is largely due to the fact that drug dosages and effects have historically been studied primarily in men. This has led to a lack of understanding of how drugs specifically affect women.
Choice B Reason:
Women do not necessarily metabolize drugs more slowly than men. Drug metabolism can vary widely depending on the specific medication and individual differences. However, the lack of female representation in clinical trials has resulted in less data on how women metabolize certain drugs, leading to unpredictable effects.
Choice C Reason:
Most known drug effects are indeed based on drug trials conducted predominantly in men. Historically, women were excluded from clinical trials due to concerns about hormonal fluctuations and potential risks to fetuses. This has resulted in a significant gap in knowledge about how drugs affect women, leading to more unpredictable and often adverse effects when these drugs are used by women.
Choice D Reason:
While hormonal fluctuations during menstrual cycles can affect drug metabolism and efficacy, this is not the primary reason for the unpredictable effects of drugs in women. The main issue is the historical exclusion of women from clinical trials, which has led to a lack of data on how drugs affect women differently from men.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","C","E"]
Explanation
Choice A Reason:
Chronic stress can significantly impact mental health, leading to conditions such as depression. The persistent activation of the stress response system, particularly the release of cortisol, can alter brain function and structure, contributing to mood disorders. Studies have shown that prolonged exposure to stress hormones can lead to changes in the brain that are associated with depression.
Choice B Reason:
Impaired cognitive function is another consequence of chronic stress. Elevated levels of cortisol over an extended period can damage the hippocampus, a region of the brain involved in memory and learning. This can result in difficulties with concentration, memory, and decision-making. Chronic stress has been linked to cognitive decline and an increased risk of neurodegenerative diseases.
Choice C Reason:
Chronic stress can also affect the immune system, leading to autoimmune diseases. The continuous activation of the stress response can cause immune dysregulation, where the body’s immune system mistakenly attacks its own tissues. This can result in conditions such as rheumatoid arthritis, lupus, and other autoimmune disorders.
Choice D Reason:
Overactive immune function is not typically associated with chronic stress. Instead, chronic stress often leads to a weakened immune response, making the body more susceptible to infections and illnesses. Therefore, this choice is incorrect.
Choice E Reason:
Cardiovascular disease is a well-documented consequence of chronic stress. The persistent release of stress hormones like adrenaline and cortisol can lead to increased blood pressure, heart rate, and the formation of artery-clogging deposits. These changes can increase the risk of heart disease, heart attacks, and strokes.
Correct Answer is D
Explanation
Choice A Reason:
Tertiary prevention focuses on managing and mitigating the complications of an existing disease to prevent further deterioration. For obesity, this might involve interventions like bariatric surgery or intensive management of comorbid conditions such as diabetes or cardiovascular disease. In this scenario, the goal is not to prevent the onset of disease but to manage its long-term effects and improve quality of life.
Choice B Reason:
Disease treatment refers to the direct management of a diagnosed condition. For a diabetic teen, this could include medications like insulin or metformin, regular monitoring of blood glucose levels, and other medical interventions to control diabetes. While a low-calorie diet and exercise are important components of diabetes management, they are more aligned with preventive measures rather than direct treatment.
Choice C Reason:
Secondary prevention aims to detect and address a disease early in its course to prevent progression. This might include screening programs, early interventions, and lifestyle modifications for individuals at high risk of developing a condition. In the context of diabetes, secondary prevention could involve regular blood glucose monitoring and early dietary changes to prevent the progression from prediabetes to diabetes.
Choice D Reason:
Primary prevention involves measures taken to prevent the onset of a disease before it occurs. This includes lifestyle interventions such as a healthy diet, regular physical activity, and maintaining a healthy weight. For an obese diabetic teen, a prescription for a low-calorie diet and exercise program is aimed at preventing further weight gain and reducing the risk of developing additional health complications, making it a primary prevention strategy.
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