Which type of cell death causes the least damage to cells that are nearby?

Choice A Reason:

Boxed warnings, also known as black box warnings, are the strictest warnings put in the labeling of prescription drugs by the FDA when there is reasonable evidence of an association of a serious hazard with the drug. However, they do not necessarily indicate that a drug should only be given in life-threatening circumstances. Instead, they highlight the potential for serious or life-threatening risks and advise on how to use the drug safely.

Choice B Reason:

While some boxed warnings may include information about teratogenic effects (effects that can cause birth defects), this is not their primary purpose. Boxed warnings are broader and can apply to various serious risks, not just teratogenicity. Therefore, this choice is too narrow to be correct.

Choice C Reason:

This is the correct answer. Boxed warnings are designed to alert prescribers to serious or life-threatening risks associated with a drug and provide guidance on how to mitigate these risks. This can include recommendations for monitoring, dosage adjustments, or avoiding certain populations. The goal is to ensure that prescribers are fully aware of the risks and can take appropriate measures to minimize harm to patients.

Choice D Reason:

Boxed warnings do not typically provide information about antidotes for toxicity. While managing toxicity is an important aspect of drug safety, boxed warnings focus on alerting prescribers to serious risks and how to mitigate them, rather than detailing specific antidotes.

Choice A Reason:

An idiosyncratic effect is an unusual or unexpected reaction to a drug that is not related to the dose and is not a common side effect. These reactions are often due to genetic differences in metabolism or immune response. In this case, shortness of breath is a known reaction for some patients taking the drug, so it is not considered idiosyncratic.

Choice B Reason:

A teratogenic effect refers to a drug’s potential to cause developmental abnormalities in a fetus when taken by a pregnant woman. Since the patient is experiencing shortness of breath, which is a known reaction to the drug, this choice is not relevant to the situation.

Choice C Reason:

This is the correct answer. A side effect is a secondary, typically undesirable effect of a drug or medical treatment. Since the nurse found that shortness of breath is a known reaction for some patients taking the drug, it is classified as a side effect. The nurse should report this to the provider to ensure proper management and monitoring.

Choice D Reason:

The symptom of shortness of breath is related to the medication administration, as confirmed by the drug administration manual. Therefore, this choice is incorrect. The nurse must report the side effect to the provider for appropriate action.