Which type of cell death causes the least damage to cells that are nearby?
Atrophy
Apoptosis
Necrosis
Lysis
The Correct Answer is B
Choice A Reason:
Atrophy refers to the reduction in size or wasting away of an organ or tissue due to a decrease in cell size or number. It is not a type of cell death but rather a process of cell shrinkage and loss of function. Therefore, it does not directly relate to the damage caused to nearby cells.
Choice B Reason:
This is the correct answer. Apoptosis is a form of programmed cell death that occurs in a controlled and regulated manner. It allows for the removal of damaged or unnecessary cells without causing an inflammatory response or damage to surrounding tissues. During apoptosis, cellular components are neatly packaged into vesicles called apoptotic bodies, which are then phagocytosed by neighboring cells or immune cells, preventing the release of harmful substances.
Choice C Reason:
Necrosis is a form of traumatic cell death that results from acute cellular injury. It often leads to the uncontrolled release of cellular contents, causing inflammation and damage to surrounding tissues. This process can be detrimental to nearby cells and is generally considered more harmful than apoptosis.
Choice D Reason:
Lysis refers to the breaking down or destruction of cells, often due to external factors such as toxins, infections, or immune responses. Like necrosis, lysis can result in the release of cellular contents into the surrounding environment, leading to inflammation and damage to nearby cells.
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Related Questions
Correct Answer is C
Explanation
Choice A Reason:
Hyperplasia refers to an increase in the number of cells in an organ or tissue, usually resulting in an increase in the size of the organ or tissue. This process is often a response to a stimulus and can be physiological or pathological. However, hyperplasia does not involve the replacement of one cell type with another, as seen in this case.
Choice B Reason:
Dysplasia is characterized by abnormal growth and development of cells within tissues or organs. It often indicates a precancerous condition and involves changes in cell size, shape, and organization. While dysplasia can occur in the respiratory tract, it does not describe the replacement of one type of epithelial cell with another.
Choice C Reason:
This is the correct answer. Metaplasia is the process by which one type of adult cell is replaced by another type of adult cell that is not typical for that tissue. In this case, the normal columnar ciliated cells in the bronchial airway have been replaced by stratified squamous epithelial cells, a common adaptation in response to chronic irritation from smoking.
Choice D Reason:
Hypertrophy refers to an increase in the size of cells, leading to an increase in the size of the affected organ or tissue. This process does not involve a change in cell type, making it an incorrect choice for this scenario.
Correct Answer is B
Explanation
Choice A Reason:
An increase in HCO3- (bicarbonate) is not typically associated with diarrhea and lower intestinal fluid losses. In fact, the opposite is true. Diarrhea often leads to a loss of bicarbonate, which can result in metabolic acidosis. Therefore, this choice is incorrect.
Choice B Reason:
This is the correct answer. Diarrhea and other lower intestinal fluid losses lead to a decrease in HCO3- levels. The loss of bicarbonate from the body results in a lower pH, contributing to metabolic acidosis. This condition occurs because bicarbonate is a key buffer that helps maintain the acid-base balance in the blood.
Choice C Reason:
An increase in the chance of alkalosis is not typically associated with diarrhea. Alkalosis refers to a condition where the pH of the blood is higher than normal, which can occur due to a loss of hydrogen ions or an increase in bicarbonate. However, diarrhea usually causes a loss of bicarbonate, leading to acidosis rather than alkalosis.
Choice D Reason:
Saying that diarrhea has no effect on the pH of the blood is incorrect. Diarrhea can significantly impact the acid-base balance in the body by causing a loss of bicarbonate, leading to metabolic acidosis. Therefore, this choice is incorrect.
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