A nurse manager is preparing to discuss methods to mitigate burnout with their staff who care for terminally ill children. Which of the following information should the nurse plan to include in the discussion? (Select All that Apply.)

A. "The life expectancy for an individual who has this disorder is 25 years of age." Advances in treatment, including improved respiratory therapies and medications like CFTR modulators, have significantly increased life expectancy. Many individuals with cystic fibrosis (CF) now live into their 40s or beyond, depending on disease severity and access to medical care.

B. "This disorder is most common in individuals of Northern European descent." CF is most prevalent in individuals of Northern European ancestry, affecting about 1 in 2,500 to 3,500 newborns in this population. It is much less common in individuals of African, Asian, or Hispanic descent.

C. "Heart failure will occur at some point during the progression of CF." CF primarily affects the lungs and digestive system due to thick mucus production, but heart failure is not a direct consequence of the disease. However, cor pulmonale (right-sided heart failure) can develop secondary to chronic lung disease and pulmonary hypertension in severe cases.

D. "This disorder occurs when the mother has a mutation of the 7th chromosome." CF is an autosomal recessive disorder, meaning a child must inherit mutated CFTR genes from both parents (not just the mother). The mutation affects the CFTR gene located on chromosome 7, leading to defective chloride transport and thick mucus production.

A. "Palliative care should be given separately from curative care." Palliative care can be provided alongside curative treatments to enhance comfort and quality of life. It is not limited to end-of-life care but focuses on symptom management and emotional support throughout the illness.

B. "Clinicians should participate in the discussion with the family about the child's prognosis." Open, honest, and compassionate communication between healthcare providers and families is crucial. Clinicians help families understand the prognosis, treatment options, and goals of care, ensuring informed decision-making.

C. "Parents who express hope of their child surviving are less accepting of palliative care." Parents can hope for a cure while still accepting palliative care to improve their child's comfort and quality of life. Hope and palliative care are not mutually exclusive.

D. "Palliative care should be offered once a child has less than 6 months to live." Palliative care is not limited to a specific timeframe. It can begin at diagnosis of a serious illness and continue throughout treatment, rather than being restricted to end-of-life care.