A nurse understands that anthelmintic drugs are contraindicated in which patients?

Choice A rationale:

Sedation Sedation is not typically associated with laxative use. Laxatives are primarily used to relieve constipation by promoting bowel movements, and sedation is not a common adverse reaction.

Choice B rationale:

Renal Impairment Renal impairment is a significant consideration when prescribing laxatives, especially those that may be excreted by the kidneys. In patients with renal impairment, there is a risk of drug accumulation, which could lead to potential adverse effects. The nurse should educate the client about this possibility to ensure their safety.

Choice C rationale:

Cramps Cramps are a possible adverse reaction to laxative use. Laxatives can cause gastrointestinal discomfort, including cramping and abdominal pain. However, it's essential to inform the client of this potential side effect so they can be prepared for it.

Choice D rationale:

Hepatic Impairment Hepatic impairment is not typically associated with adverse reactions to laxative use. Laxatives primarily affect the gastrointestinal system and do not directly impact the liver. Therefore, hepatic impairment is not a major concern when using laxatives.

Choice A rationale:

Aminoglycosides are known to have nephrotoxic effects. Nephrotoxicity refers to kidney toxicity, and aminoglycosides can cause damage to the renal tubules, leading to impaired kidney function. The nurse should be alert to this potential toxicity when administering these drugs, as it can result in kidney dysfunction, altered serum creatinine levels, and electrolyte imbalances.

Choice B rationale:

Cardiotoxicity is not typically associated with aminoglycosides. These antibiotics primarily affect the kidneys and the inner ear. There is no direct relationship between aminoglycosides and cardiac toxicity.

Choice C rationale:

Hepatotoxicity refers to liver toxicity and is not a common side effect of aminoglycosides. Aminoglycosides are primarily metabolized in the kidneys and are excreted through urine, making kidney toxicity a more significant concern.

Choice D rationale:

Cytotoxicity is a broad term that refers to the toxicity of cells. Aminoglycosides do not typically cause generalized cytotoxic effects in the body. Their primary toxicities are related to specific organ systems, such as the kidneys and the inner ear.