A patient is admitted to the emergency department (ED) following an overdose of acetaminophen (Tylenol) and is diagnosed with cirrhosis. Which laboratory finding is consistent with the diagnosis?

A. Diminished serum albumin levels cause water to shift from blood to tissue: In cirrhosis, liver dysfunction leads to decreased production of albumin, a protein that helps maintain oncotic pressure. Low albumin levels cause fluid to shift from the vascular space into the tissues, resulting in ascites and peripheral edema.

B. Portal hypotension causes a fluid shift from the abdominal cavity into the portal veins: Portal hypertension, not hypotension, is a common feature of cirrhosis, but it leads to ascites by increasing pressure in the portal venous system, not by shifting fluid into the portal veins.

C. Hypoaldosteronism causes a fluid volume deficit: shifting water from blood into tissue: Cirrhosis often leads to hyperaldosteronism, not hypoaldosteronism, resulting in sodium and water retention, which contributes to edema.

D. Aberrations of the portal system cause a back-up of blood that leads to hydronephrosis: Hydronephrosis is related to obstruction of the urinary tract, not a complication of portal hypertension or cirrhosis.

A. Decrease osteoclastic activity: Osteoporosis treatments often focus on reducing osteoclastic activity, which is responsible for bone resorption, thereby helping to maintain or increase bone density.

B. Increase the kidneys' tubular secretion of calcium into the urine: This would decrease calcium levels in the body, which is not desired in osteoporosis treatment, as it would worsen bone density.

C. Increase resorption of calcium: Increasing bone resorption would exacerbate osteoporosis by weakening the bones further.

D. Suppress calcitonin: Calcitonin helps to inhibit bone resorption, so suppressing it would be counterproductive in treating osteoporosis.