A patient states, "I feel detached from myself and weird all the time. It is as though I am looking at life through a cloudy window. Everything seems unreal. It really messes up things at work and school." This scenario is most suggestive of which health problem?
Dissociative amnesia.
Depersonalization disorder.
Acute stress disorder.
Disinhibited social engagement disorder.
The Correct Answer is B
Choice A reason: Dissociative amnesia involves memory loss for specific events, linked to hippocampal dysfunction and stress-induced cortisol elevation. The patient’s persistent detachment and unreality feelings do not indicate memory loss but rather altered temporoparietal neural activity, making amnesia an incorrect diagnosis for the described symptoms.
Choice B reason: Depersonalization disorder involves persistent feelings of detachment and unreality, driven by disrupted temporoparietal cortex activity and altered serotonin signaling. The patient’s description of feeling detached and life seeming unreal aligns with this condition, reflecting neurochemical imbalances affecting perception and emotional integration.
Choice C reason: Acute stress disorder involves trauma-related symptoms like hyperarousal or dissociation within a month of trauma, driven by amygdala hyperactivity. The patient’s chronic detachment suggests a persistent condition, not time-limited, making depersonalization disorder more likely than acute stress disorder’s transient neural dysregulation.
Choice D reason: Disinhibited social engagement disorder, seen in children post-trauma, involves inappropriate social familiarity, linked to amygdala-prefrontal dysregulation. The patient’s symptoms of detachment and unreality are unrelated to social behavior, making this diagnosis inappropriate, as it does not involve temporoparietal perceptual distortions.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason: Anger involves resentment or frustration, driven by amygdala hyperactivity and norepinephrine surges. The husband’s calm acknowledgment of death reflects acceptance, not anger, indicating resolved emotional processing, not ongoing neural distress.
Choice B reason: Depression involves sadness and despair, with low serotonin and amygdala-driven grief. The husband’s statement reflects peace and acceptance, not depressive symptoms, indicating he has moved beyond this stage to neural emotional stability.
Choice C reason: Bargaining involves seeking to delay death, driven by amygdala-anxiety and cortisol release. The husband’s statement accepts the inevitability of death, reflecting prefrontal cortex-mediated resolution, not ongoing neural attempts to negotiate or delay.
Choice D reason: Acceptance, per Kubler-Ross, involves acknowledging death calmly, as shown by the husband’s statement. This reflects balanced amygdala-prefrontal cortex processing, with serotonin-mediated emotional stability, indicating resolution of grief and acceptance of the inevitable.
Correct Answer is C
Explanation
Choice A reason: Aripiprazole, an antipsychotic, may cause dystonic reactions via partial dopamine agonism. It is not used to treat dystonia, as it could worsen extrapyramidal symptoms by altering basal ganglia dopamine signaling, making it inappropriate for acute dystonic reaction management.
Choice B reason: Risperidone, an antipsychotic, can cause dystonic reactions due to dopamine D2 receptor blockade in the basal ganglia. Administering it would exacerbate extrapyramidal symptoms, not relieve them, making it unsuitable for treating acute dystonic reactions.
Choice C reason: Diphenhydramine, an antihistamine with anticholinergic properties, relieves dystonic reactions by counteracting dopamine blockade-induced basal ganglia dysfunction. It restores cholinergic-dopaminergic balance, reducing muscle spasms and rigidity, making it the standard treatment for antipsychotic-induced acute dystonic reactions.
Choice D reason: Propranolol, a beta-blocker, treats tremors or hypertension but not dystonic reactions, which stem from dopamine-cholinergic imbalance in the basal ganglia. It lacks anticholinergic effects needed to reverse dystonia, making it ineffective for this antipsychotic-related side effect.
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