A patient who takes warfarin (Coumadin) is brought to the emergency department after accidentally taking too much warfarin. The patient's heart rate is 78 beats per minute and the blood pressure is 120/80 mm Hg. Dipstick urinalysis is normal. The patient does not have any signs of bleeding and does not complain of pain. The nurse will anticipate an order for:
vitamin K (phytonadione)
protamine sulfate
a PTT lab test
an INR lab test
The Correct Answer is A
Choice A reason:
Vitamin K (phytonadione) is the antidote for warfarin overdose. It works by promoting the synthesis of clotting factors that are inhibited by warfarin, thereby reversing the anticoagulant effects. In cases of excessive warfarin intake, administering vitamin K helps restore normal clotting function.
Choice B reason:
Protamine sulfate is the antidote for heparin overdose, not warfarin. It works by neutralizing the anticoagulant effects of heparin, but it has no effect on warfarin-induced anticoagulation. Therefore, it is not appropriate for this situation.
Choice C reason:
A PTT lab test measures the effectiveness of the intrinsic pathway of coagulation and is primarily used to monitor heparin therapy. It is not relevant for managing warfarin overdose, as warfarin affects the extrinsic pathway, which is measured by the PT/INR test.
Choice D reason:
While an INR lab test is essential for monitoring the therapeutic levels of warfarin, the immediate need in this situation is to reverse the effects of the overdose. Administering vitamin K is the necessary intervention to counteract the excessive anticoagulation caused by warfarin.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason:
Fatty acids are essential components of many lipids, but they are not the primary building blocks of bile salts. Bile salts are synthesized from cholesterol. Fatty acids mainly function as energy storage molecules and are involved in forming complex lipids, like triglycerides and phospholipids. They don't participate directly in the production of bile salts, which are crucial for digesting and absorbing dietary fats.
Choice B reason:
Testosterone is a steroid hormone that plays a vital role in male reproductive tissues and secondary sexual characteristics. It is not involved in the synthesis of bile salts. Bile salts are derived from cholesterol, not hormones. Testosterone’s primary function is related to endocrine activities rather than hepatic functions like bile salt synthesis.
Choice C reason:
Cholesterol is the correct answer. Bile salts are synthesized from cholesterol in the liver. This process involves the conversion of cholesterol into bile acids, which are then conjugated with amino acids to form bile salts. These bile salts are critical for the digestion and absorption of fats in the small intestine. The liver’s conversion of cholesterol to bile salts helps in maintaining cholesterol homeostasis in the body.
Choice D reason:
Lecithin is a type of phospholipid that plays a significant role in cell membrane structure and function. While it is an important component of bile, it is not the substance from which bile salts are synthesized. Lecithin helps in the emulsification of fats in the digestive process but is not a precursor to bile salts. The synthesis of bile salts specifically involves cholesterol.
Correct Answer is A
Explanation
Choice A reason:
Lactulose is the medication of choice for treating elevated ammonia levels, commonly seen in hepatic encephalopathy associated with cirrhosis. It works by reducing the absorption of ammonia from the intestines, converting ammonia to ammonium, which is then excreted. Administering lactulose helps in lowering blood ammonia levels and improving mental status in affected patients.
Choice B reason:
Polyethylene glycol (MiraLax) is a laxative used to treat constipation. It does not have any role in reducing ammonia levels or treating hepatic encephalopathy. Therefore, it is not appropriate for this patient's elevated ammonia condition.
Choice C reason:
0.9% NS (normal saline) is primarily used for fluid resuscitation and electrolyte balance. While essential in managing cirrhotic patients with fluid imbalances, it does not address the elevated ammonia levels directly. Therefore, it is not the treatment of choice for this specific situation.
Choice D reason:
Docusate sodium (Colace) is a stool softener used to treat constipation. It does not have any effect on ammonia levels or the treatment of hepatic encephalopathy. Thus, it is not appropriate for managing elevated ammonia in this patient.
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