A patient with chronic kidney disease (CKD) is being evaluated for medication management. Which of the following medications should be avoided due to its potential nephrotoxic effects?
Atorvastatin
Losartan
Vancomycin
Aspirin
The Correct Answer is C
A. Atorvastatin: Atorvastatin is a statin used to manage cholesterol levels. It is generally safe for use in patients with CKD.
B. Losartan: Losartan is an angiotensin II receptor blocker (ARB) used to manage hypertension and protect the kidneys in diabetic nephropathy. It can be beneficial in CKD patients.
C. Vancomycin: Vancomycin is an antibiotic known to be nephrotoxic, especially in patients with compromised kidney function. It should be used with caution or avoided in patients with CKD.
D. Aspirin: While aspirin can have adverse effects on the kidneys at high doses, its nephrotoxic potential is lower than that of vancomycin. In low doses, aspirin is commonly used for cardiovascular protection, even in patients with CKD.
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Related Questions
Correct Answer is C
Explanation
A. Atorvastatin: Atorvastatin is a statin used to manage cholesterol levels. It is generally safe for use in patients with CKD.
B. Losartan: Losartan is an angiotensin II receptor blocker (ARB) used to manage hypertension and protect the kidneys in diabetic nephropathy. It can be beneficial in CKD patients.
C. Vancomycin: Vancomycin is an antibiotic known to be nephrotoxic, especially in patients with compromised kidney function. It should be used with caution or avoided in patients with CKD.
D. Aspirin: While aspirin can have adverse effects on the kidneys at high doses, its nephrotoxic potential is lower than that of vancomycin. In low doses, aspirin is commonly used for cardiovascular protection, even in patients with CKD.
Correct Answer is D
Explanation
A. The patients have lowered their cholesterol levels from previous laboratory results: Lower cholesterol levels are a positive health outcome but could result from factors other than weight loss, such as medication or diet changes. It is a good sign but not the most direct measure of the intervention's success.
B. The patients have improved blood pressure readings to be within expected reference range: Blood pressure improvements are important and can result from weight loss, but other factors like medications could influence this outcome.
C. The patients are choosing healthier food options for their diet plans: While choosing healthier food options is a positive behavior change, it is a process measure rather than an outcome. It does not necessarily indicate the interventions are working as effectively as a decrease in BMI.
D. There is a significant decrease in the patients' BMI measurements. A significant reduction in BMI is the most direct indicator of effective weight-loss interventions. A decrease in BMI reflects a measurable outcome that directly relates to weight loss.
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