A prescriber has ordered medication for a newborn that is eliminated primarily by hepatic metabolism. What would the nurse expect the prescriber to order?

A Increase the frequency of medication dosing.

B Order a dose that is higher than an adult dose.

Discontinue the drug after one or two treatments.

D Order a dose that is lower than an adult dose.

Answer and Explanation

The Correct Answer is D

a) Increasing the frequency of medication dosing may lead to higher overall exposure and is not necessarily related to hepatic metabolism.

b) Ordering a dose that is higher than an adult dose could result in excessive drug levels, especially in a newborn with immature hepatic function.

c) Discontinuing the drug after one or two treatments may not be necessary if the dose is appropriately adjusted based on hepatic metabolism.

d) Ordering a lower dose is appropriate because hepatic metabolism in newborns is often immature, and lower doses are required to avoid toxicity.

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Correct Answer is A

Explanation

a) St. John's Wort is known to increase the risk of bleeding, especially when used with anticoagulant medications. This effect is particularly concerning and may require adjustments in the treatment plan.

b) While St. John's Wort can interact with various drugs, increasing the risk of bleeding is a more immediate concern.

c) St. John's Wort does not counteract the effects of CNS depressants; it may actually enhance the effects of these drugs.

d) St. John's Wort is known to induce the metabolism of some drugs, potentially reducing their effectiveness, but this is not as immediately concerning as the risk of bleeding.

A. Avoid salt substitutes. B. Discontinue taking this medication if you feel well. C. Add as many fruits and vegetables to your diet as possible. D. Check your pulse before taking this medication.

Correct Answer is A

Explanation

a) Spironolactone is a potassium-sparing diuretic, and the use of salt substitutes, which often contain potassium chloride, can lead to increased potassium levels, posing a risk of hyperkalemia.

b) Continuing medication even when feeling well is generally advised, especially for chronic conditions. Discontinuing medication without medical guidance is not recommended. c) While a healthy diet is important, this option does not specifically address the unique considerations related to spironolactone use.

d) Checking the pulse is not directly related to self-care in terms of the medication's side effects or interactions.

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A prescriber has ordered medication for a newborn that is eliminated primarily by hepatic metabolism. What would the nurse expect the prescriber to order?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is obtaining a history from a client who discloses daily use of St. John's Wort in addition to prescription drugs. Which effect of this dietary supplement would most concern the nurse?

Correct Answer is A

Explanation

What should the nurse advise a client on spironolactone regarding necessary self-care?

Correct Answer is A

Explanation

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