A student asked the pharmacology instructor to describe the function of a cholinergic agonist.
What would be the instructor’s reply?
Cholinergic agonist decreases the activity of gamma-aminobutyric acid (GABA) receptor sites throughout the body.
Cholinergic agonist decreases the activity of norepinephrine throughout the body.
Cholinergic agonist increases the activity of dopamine receptor sites throughout the brain and spinal cord.
Cholinergic agonist increases the activity of acetylcholine receptor sites throughout the body.
The Correct Answer is D
Choice A rationale
This choice is incorrect. Cholinergic agonists primarily affect acetylcholine receptors, not GABA receptors. GABA receptors are involved in the inhibitory neurotransmission in the central nervous system and are the target of different drug classes, such as benzodiazepines and barbiturates, which are not related to cholinergic agonists.
Choice B rationale
This choice is incorrect. Cholinergic agonists do not decrease norepinephrine activity. Norepinephrine is a neurotransmitter involved in the sympathetic nervous system response, which is different from the cholinergic system. Drugs that decrease norepinephrine activity would have a different mechanism of action, such as adrenergic antagonists.
Choice C rationale
This choice is incorrect. The primary action of cholinergic agonists is not to increase dopamine activity. Dopamine is another neurotransmitter involved in various brain functions, including reward and motor control. Cholinergic agonists specifically target acetylcholine receptors, enhancing their activity, which is not related to dopamine receptors.
Choice D rationale
This choice is correct. Cholinergic agonists increase the activity of acetylcholine receptor sites throughout the body. These drugs mimic the action of acetylcholine, a neurotransmitter that plays a key role in the parasympathetic nervous system, which regulates functions such as muscle contraction, gland secretion, and heart rate. Enhancing acetylcholine activity helps in conditions like myasthenia gravis and certain types of glaucoma.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
Sympathetic stimulation typically increases the depth and rate of respirations to enhance oxygen delivery to tissues during stress or physical activity.
Choice B rationale
Sympathetic stimulation does not directly increase lung perfusion. It primarily affects the airways to increase airflow.
Choice C rationale
Sympathetic stimulation increases the respiratory rate by activating the respiratory centers in the brain, preparing the body for increased oxygen demand during stress or physical activity.
Choice D rationale
Sympathetic stimulation does not decrease the respiratory rate. It typically increases both the rate and depth of respirations to meet the body's increased oxygen needs. .
Correct Answer is C
Explanation
Choice A rationale
Class I antiarrhythmic drugs block sodium channels, affecting phase 0 of the action potential, not phase 3.
Choice B rationale
Class IV antiarrhythmic drugs block calcium channels, which affects phase 2 of the action potential and slows heart rate and conduction.
Choice C rationale
Class III antiarrhythmic drugs block potassium channels, prolonging phase 3 of the action potential. This results in a prolonged repolarization period, reducing the risk of arrhythmia.
Choice D rationale
Class II antiarrhythmic drugs are beta-blockers that primarily affect phase 4 of the action potential, reducing heart rate and conduction, but they do not block potassium channels.
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