A student asked the pharmacology instructor to describe the function of a cholinergic agonist.
What would be the instructor’s reply?
Cholinergic agonist decreases the activity of gamma-aminobutyric acid (GABA) receptor sites throughout the body.
Cholinergic agonist decreases the activity of norepinephrine throughout the body.
Cholinergic agonist increases the activity of dopamine receptor sites throughout the brain and spinal cord.
Cholinergic agonist increases the activity of acetylcholine receptor sites throughout the body.
The Correct Answer is D
Choice A rationale
This choice is incorrect. Cholinergic agonists primarily affect acetylcholine receptors, not GABA receptors. GABA receptors are involved in the inhibitory neurotransmission in the central nervous system and are the target of different drug classes, such as benzodiazepines and barbiturates, which are not related to cholinergic agonists.
Choice B rationale
This choice is incorrect. Cholinergic agonists do not decrease norepinephrine activity. Norepinephrine is a neurotransmitter involved in the sympathetic nervous system response, which is different from the cholinergic system. Drugs that decrease norepinephrine activity would have a different mechanism of action, such as adrenergic antagonists.
Choice C rationale
This choice is incorrect. The primary action of cholinergic agonists is not to increase dopamine activity. Dopamine is another neurotransmitter involved in various brain functions, including reward and motor control. Cholinergic agonists specifically target acetylcholine receptors, enhancing their activity, which is not related to dopamine receptors.
Choice D rationale
This choice is correct. Cholinergic agonists increase the activity of acetylcholine receptor sites throughout the body. These drugs mimic the action of acetylcholine, a neurotransmitter that plays a key role in the parasympathetic nervous system, which regulates functions such as muscle contraction, gland secretion, and heart rate. Enhancing acetylcholine activity helps in conditions like myasthenia gravis and certain types of glaucoma.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
Monitoring the weekly pulse is not sufficient for managing ventricular arrhythmias at home. Continuous or daily monitoring of vital parameters is more effective.
Choice B rationale
Monitoring daily fluid intake is essential for overall health but not directly related to the management of ventricular arrhythmias with propranolol (Inderal).
Choice C rationale
Daily blood pressure monitoring is crucial for patients on propranolol, as this medication can significantly lower blood pressure, and tracking it helps prevent hypotension.
Choice D rationale
Weekly weight monitoring is important for patients with heart conditions, but daily monitoring of blood pressure is more directly related to the management of ventricular arrhythmias with propranolol.
Correct Answer is D
Explanation
Choice A rationale
Schedule I drugs have no medical use and high abuse potential, unlike morphine.
Choice B rationale
Schedule III drugs have less abuse potential than Schedule II, making this incorrect for morphine.
Choice C rationale
Schedule IV drugs have even lower abuse potential, incorrect for morphine.
Choice D rationale
Schedule II drugs have high abuse potential with medical use, fitting morphine's classification.
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