A nurse is providing discharge teaching for a patient who will be going home on cyclobenzaprine (Flexeril) prescribed for his acute musculoskeletal pain.
The nurse will stress that the patient should avoid what?

Choice A rationale

Working with animals is typically done in preclinical trials before phase I studies in humans and is not part of phase III drug evaluation studies.

Choice B rationale

Conducting research to determine the effectiveness of the drug is part of phase II studies. Phase III studies focus more on confirming effectiveness, monitoring side effects, and comparing it to commonly used treatments.

Choice C rationale

Monitoring and observing patients closely for adverse effects is a key responsibility in phase III drug evaluation studies. These studies involve a larger patient population to gather comprehensive safety and efficacy data.

Choice D rationale

Choosing appropriate patients to be involved in the study is primarily the responsibility of researchers and clinicians during the earlier phases of drug development, such as phase I and phase II studies.

Choice A rationale

Narcotic agents are commonly prescribed for the relief of moderate to severe acute pain.

Choice B rationale

Narcotic agents are not typically used for minor pain due to the risk of dependency and side effects.

Choice C rationale

Analgesia during sleep is not a usual indication for narcotics as their primary use is for pain relief.

Choice D rationale

Narcotics may be used during anesthesia, but the primary reason is pain relief. .