How do we measure inflammation? (Select all that apply)

Choice A reason: The nasal compartment refers to the nasal cavity, not specific colored areas. Paranasal sinuses are air-filled cavities around the nose, often highlighted in anatomical diagrams, making this an incorrect term for the described structures.

Choice B reason: Paranasal sinuses, including frontal, ethmoid, sphenoid, and maxillary sinuses, are air-filled cavities around the nasal cavity, often colored in anatomical images. This matches the question’s reference to colored areas, making it the correct term.

Choice C reason: Runny nose describes a symptom (rhinorrhea), not anatomical structures. The question refers to colored areas, likely in a diagram, which aligns with sinuses, not a clinical condition, making this an incorrect choice.

Choice D reason: Olfactory bulbs are neural structures for smell, located above the nasal cavity, not typically colored as distinct areas in sinus diagrams. Paranasal sinuses are the highlighted structures, making this an incorrect term for the described areas.

Choice A reason: Increased permeability and leakage occur at an injury site due to histamine and cytokine release, causing endothelial gaps. This allows plasma and immune cells to enter tissues, promoting inflammation and edema, making this a correct vascular change.

Choice B reason: Blood vessels initially constrict to limit bleeding, then dilate to increase blood flow, delivering immune cells and nutrients. This biphasic response (constriction followed by dilation) is a hallmark of acute injury, making this a correct vascular change.

Choice C reason: Pallor occurs from initial vasoconstriction, reducing blood flow, followed by swelling from increased permeability and fluid leakage. These are typical injury responses, reflecting vascular and tissue changes, making this a correct observation.

Choice D reason: “None of the above” is incorrect, as increased permeability, biphasic vessel response, and pallor with swelling are well-documented vascular changes at injury sites. These align with the inflammatory process, making this an invalid choice.

Choice E reason: Tightening of capillary endothelial junctions does not occur during acute injury. Junctions loosen due to inflammatory mediators, increasing permeability, not tightening, which would limit leakage, making this an incorrect vascular change.