Identify one indicator for a narcotic antagonist to be prescribed?

A) Norepinephrine: Norepinephrine is a neurotransmitter primarily involved in the sympathetic nervous system. It is not involved in terminating the stimulation caused by acetylcholine. Norepinephrine acts on adrenergic receptors, whereas acetylcholine primarily acts on cholinergic receptors.
B) Decarboxylase: Decarboxylase is an enzyme that plays a role in the synthesis of certain neurotransmitters, including dopamine, but it does not have a role in terminating the action of acetylcholine at the effector cell. It is unrelated to the termination of acetylcholine signaling.
C) Catecholamine: Catecholamines (such as dopamine, norepinephrine, and epinephrine) are a group of neurotransmitters involved in the sympathetic nervous system. While they play a role in synaptic transmission, they are not responsible for breaking down acetylcholine or terminating its effects. Their primary function is in adrenergic signaling.
D) Acetylcholinesterase: Acetylcholinesterase is the correct enzyme. It is responsible for breaking down acetylcholine (ACh) in the synaptic cleft after it has stimulated the effector cell. By hydrolyzing acetylcholine into acetate and choline, acetylcholinesterase effectively terminates the signal and allows the effector cell's membrane to repolarize. This action prevents continuous stimulation and ensures proper function of the cholinergic system.

A) Sweating: Sweating is a function of the sympathetic nervous system, not the parasympathetic nervous system. The sympathetic nervous system is responsible for the "fight or flight" response, which includes activating sweat glands. The parasympathetic system, in contrast, is more involved in "rest and digest" functions.

B) Pupil dilation: Pupil dilation (mydriasis) is mediated by the sympathetic nervous system through the activation of alpha-1 adrenergic receptors. The parasympathetic system causes pupil constriction (miosis) by stimulating muscarinic receptors in the eye, which is the opposite of pupil dilation.

C) Vasoconstriction: Vasoconstriction (narrowing of blood vessels) is generally a
function of the sympathetic nervous system, which releases norepinephrine to constrict blood vessels and increase blood pressure. The parasympathetic system typically causes vasodilation (widening of blood vessels) to promote relaxation and decreased blood pressure.

D) Anabolism: Anabolism refers to the metabolic processes that build up molecules and store energy, such as protein synthesis, cell growth, and energy storage. This is primarily mediated by the parasympathetic nervous system, which is involved in "rest and digest" functions. The parasympathetic system promotes activities that support energy conservation, digestion, and tissue repair, all of which support anabolic processes.