A neonate born with ambiguous genitalia is diagnosed with congenital adrenal hyperplasia (CAH). This is an autosomal recessive disorder which causes an overproduction of:
Androgens
Vitamin K
Gonadotropin
Vitamin D
The Correct Answer is A
The correct answer is a) Androgens.
Choice A reason:
Congenital adrenal hyperplasia (CAH) is a group of genetic disorders affecting the adrenal glands, which are responsible for producing vital hormones such as cortisol, aldosterone, and androgens. In CAH, there is a deficiency of the enzyme 21-hydroxylase, which is crucial for the synthesis of cortisol and aldosterone. As a result, the adrenal glands overproduce androgens, leading to symptoms such as ambiguous genitalia in newborns, early puberty, and rapid growth. Androgens are male sex hormones, including testosterone, which play a significant role in the development of male characteristics.
Choice B reason:
Vitamin K is a fat-soluble vitamin essential for blood clotting and bone health. It is not related to the overproduction of hormones in congenital adrenal hyperplasia. Vitamin K deficiency can lead to bleeding disorders, but it does not cause the symptoms associated with CAH, such as ambiguous genitalia or early puberty. Therefore, this choice is incorrect.
Choice C reason:
Gonadotropins are hormones produced by the pituitary gland that stimulate the gonads (ovaries and testes) to produce sex hormones and gametes (eggs and sperm). While gonadotropins play a role in sexual development and reproduction, they are not overproduced in congenital adrenal hyperplasia. The primary issue in CAH is the overproduction of androgens due to enzyme deficiencies in the adrenal glands. Therefore, this choice is incorrect.
Choice D reason:
Vitamin D is a fat-soluble vitamin essential for calcium absorption and bone health. It is not related to the overproduction of hormones in congenital adrenal hyperplasia. Vitamin D deficiency can lead to bone disorders such as rickets in children and osteomalacia in adults, but it does not cause the symptoms associated with CAH. Therefore, this choice is incorrect.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason:
Marbles are not a safe play activity for a 3-year-old in a spica cast. Marbles are small and can pose a choking hazard. Additionally, playing with marbles requires fine motor skills and movement that may be restricted by the cast.
Choice B Reason:
Watching a movie is a safe activity but does not provide developmental benefits. While it can keep the child entertained, it does not engage the child in active play or promote cognitive and motor development.
Choice C Reason:
A game of checkers may be too advanced for a 3-year-old. It requires understanding of rules and strategic thinking, which may be beyond the developmental stage of a child this age. Additionally, it may not be engaging enough to hold the child’s attention.
Choice D Reason:
Playing with a toy telephone is an appropriate activity for a 3-year-old in a spica cast. It is safe and can be done while the child is in a stationary position. This activity encourages imaginative play and can help with language development and social skills.
Correct Answer is ["2"]
Explanation
Calculation Steps
Step 1: Determine the total urine output in mL.
- Total urine output = 360 mL
Step 2: Determine the child’s weight in kg.
- Weight = 15 kg
Step 3: Determine the time period in hours.
- Time = 12 hours
Step 4: Calculate the urine output in mL/kg/hour.
- Urine output (mL/kg/hour) = Total urine output ÷ (Weight × Time)
Step 5: Perform the multiplication inside the parentheses first.
- Weight × Time = 15 kg × 12 hours = 180 kg·hours
Step 6: Perform the division.
- Urine output (mL/kg/hour) = 360 mL ÷ 180 kg·hours = 2 mL/kg/hour
Result
The child’s urine output is 2 mL/kg/hour.
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